TGFB1 and ANGPTL4

  • Data Source:
  • BioGRID (two hybrid)

TGFB1

ANGPTL4

Description transforming growth factor beta 1 angiopoietin like 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Coronary artery disease ( 29212778)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • HDL cholesterol ( 24097068 28270201 24507774 19060906 30275531 25961943 20686565)
  • HDL cholesterol levels ( 32203549 28334899 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Mean spheric corpuscular volume ( 32888494)
  • Metabolic syndrome ( 31589552)
  • Metabolite levels (lipoprotein measures) ( 27005778)
  • Phospholipid levels in large HDL ( 29084231)
  • Red cell distribution width ( 32888494)
  • Reticulocyte count ( 32888494)
  • Reticulocyte fraction of red cells ( 32888494)
  • Total cholesterol levels in HDL ( 29084231)
  • Total triglycerides levels ( 29084231)
  • Triglyceride levels ( 32203549 32154731 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglycerides ( 24507774 30275531 25961943 27036123)
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes 95 interacting genes: ACVRL1 ADAMTSL4 AGR3 ANGPTL4 APC APP AURKA AXIN2 BCAS3 BCL10 BGN BLID BMP2 BMP3 BMPR1A BUB1 CATSPER1 CCDC33 CCL3 CCL5 CCN2 CDKN2A COL2A1 CST6 CYSRT1 DAXX DCN DIRAS3 DLC1 DPT EGFR EIF3I ENG ERBB2 FBXW7 FCHO1 FCN1 FKBP1A FMOD FNTA GREB1 HOXA1 HOXC6 ITGAV ITGB6 ITGB8 KLK5 KLK7 KLK9 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP4-11 LAMTOR5 LCE1A LCE1C LCE1D LCE2B LCE2C LCE3A LCE3B LCE3D LPXN LTBP1 LTBP3 LTBP4 MCC MEOX2 MLH3 MMP2 MTA3 NSD3 P4HB PDGFRL PDLIM2 POU4F2 PRSS50 PSMC3IP PZP RAPGEF3 SCGB3A1 SDC2 SNAI1 SPARC ST14 TGFB2 TGFBR1 TGFBR2 TGFBR3 THBS1 THRSP TLR2 VASN VTN YWHAE 9 interacting genes: AURKA BRMS1 CASP8 CDKN2A CDKN2C ESR1 FBXW7 FGFR4 TGFB1
Entrez ID 7040 51129
HPRD ID 01821 16173
Ensembl ID ENSG00000105329 ENSG00000167772
Uniprot IDs A0A499FJK2 P01137 Q9BY76
PDB IDs 1KLA 1KLC 1KLD 3KFD 4KV5 5FFO 5VQP 6OM2 6P7J 6EUB 6U0A 6U1U 6U73
Enriched GO Terms of Interacting Partners?
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