CNTN2 and NFYB

Data Source:
HPRD (two hybrid, in vivo)

		CNTN2	NFYB
Description		contactin 2	nuclear transcription factor Y subunit beta
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GO Annotations	Cellular Component	Plasma Membrane Axon Node Of Ranvier Myelin Sheath Juxtaparanode Region Of Axon Synapse Anchored Component Of Postsynaptic Membrane	Chromatin Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Protein Binding Identical Protein Binding Cell-cell Adhesion Mediator Activity	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity Repressing Transcription Factor Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Clustering Of Voltage-gated Potassium Channels Dendrite Self-avoidance Protein Localization To Juxtaparanode Region Of Axon Presynaptic Membrane Organization	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II
Pathways		L1CAM interactions NCAM1 interactions NrCAM interactions	PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Blood protein levels ( 30072576 29875488 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) HDL cholesterol levels ( 32203549) Mean platelet volume ( 24026423) Meat-related diet ( 32066663) Number of sexual partners ( 30643258) Red blood cell count ( 27863252) Schizophrenia ( 30285260) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Toenail selenium levels ( 25343990)
Interacting Genes		11 interacting genes: CDK4 CHEK1 CNTN1 CNTNAP2 EGFR L1CAM NCAN NFYB NRCAM TUBG1 VAC14	26 interacting genes: AGTRAP C1QBP CEBPZ CIITA CNTN2 DRAP1 ELF1 EP300 GRB2 MAOB MEOX2 MYC NFYA NFYC POLE4 POU3F2 SMYD3 SP1 TAF11 TAF12 TAF6 TBP TP53 TP73 YBX1 YBX3
Entrez ID		6900	4801
HPRD ID		01826	01794
Ensembl ID		ENSG00000184144	ENSG00000120837
Uniprot IDs		A1L3A3 A1ML24 Q02246	A0A024RBG7 F8VSL3 P25208
PDB IDs		2OM5	1N1J 4AWL 4CSR 6QMP 6QMQ 6QMS
Enriched GO Terms of Interacting Partners?
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