VAMP1 and SNAP23

Data Source:
HPRD (two hybrid, in vitro)

		VAMP1	SNAP23
Description		vesicle associated membrane protein 1	synaptosome associated protein 23
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane SNARE Complex Azurophil Granule Membrane Specific Granule Membrane Neuron Projection Tertiary Granule Membrane	Nucleoplasm Cytoplasm Mitochondrion Plasma Membrane Adherens Junction Focal Adhesion Phagocytic Vesicle Membrane SNARE Complex Specific Granule Membrane Specific Granule Azurophil Granule Neuron Projection Extracellular Exosome Tertiary Granule Membrane Presynapse
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Vesicle Fusion SNARE Complex Assembly	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Histamine Secretion By Mast Cell Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Targeting Vesicle Fusion Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Membrane Fusion
Pathways		Toxicity of botulinum toxin type D (botD) Toxicity of botulinum toxin type F (botF) Toxicity of botulinum toxin type G (botG)	ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Neutrophil degranulation
Drugs		Botulinum Toxin Type B
Diseases
GWAS		Hip geometry ( 17903296)	Bipolar disorder ( 31043756)
Interacting Genes		36 interacting genes: AQP6 ARL13B BCAP31 CDKN2A CRB3 CREB3L1 CYB5R3 DNAJC5 EBP ELOVL4 ELOVL7 ERGIC3 FAM210B FCER1G GPR152 KASH5 LAPTM5 LMNA REEP4 RETREG3 RNF24 SCN3B SEC11C SGMS2 SLC30A8 SNAP23 SNAP29 STX1A STX1B STX4 TMEM101 TMEM14B TMEM35A TMX2 VAPA VAPB	32 interacting genes: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP7 VAMP8 WASH2P
Entrez ID		6843	8773
HPRD ID		01716	03962
Ensembl ID		ENSG00000139190	ENSG00000092531
Uniprot IDs		F5GZV7 P23763	A0A024R9R8 A8K287 O00161
PDB IDs			1NHL 3ZUS
Enriched GO Terms of Interacting Partners?
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