VAMP1 and CYB5R3

Data Source:
BioGRID (two hybrid)

		VAMP1	CYB5R3
Description		vesicle associated membrane protein 1	cytochrome b5 reductase 3
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane SNARE Complex Azurophil Granule Membrane Specific Granule Membrane Neuron Projection Tertiary Granule Membrane	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen Nitric-oxide Synthase Complex
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding Nitrite Reductase (NO-forming) Activity NAD Binding FAD Binding
	Biological Process	Vesicle Fusion SNARE Complex Assembly	Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Blood Circulation L-ascorbic Acid Metabolic Process Neutrophil Degranulation
Pathways		Toxicity of botulinum toxin type D (botD) Toxicity of botulinum toxin type F (botF) Toxicity of botulinum toxin type G (botG)	Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs		Botulinum Toxin Type B	NADH Flavin adenine dinucleotide Copper
Diseases			Methemoglobinemia
GWAS		Hip geometry ( 17903296)	Initial pursuit acceleration ( 29064472)
Interacting Genes		36 interacting genes: AQP6 ARL13B BCAP31 CDKN2A CRB3 CREB3L1 CYB5R3 DNAJC5 EBP ELOVL4 ELOVL7 ERGIC3 FAM210B FCER1G GPR152 KASH5 LAPTM5 LMNA REEP4 RETREG3 RNF24 SCN3B SEC11C SGMS2 SLC30A8 SNAP23 SNAP29 STX1A STX1B STX4 TMEM101 TMEM14B TMEM35A TMX2 VAPA VAPB	61 interacting genes: ADAM33 AGTRAP AIG1 ALG8 AQP6 ASGR1 BNIP2 CDIPT CERS4 CNIH1 COL8A2 CSGALNACT2 CYB5A CYCS ELOVL4 FAM210B FAM3C FAXDC2 FUNDC2 FXYD3 GAST GPR152 GRM2 HBG2 HSD17B13 LAPTM5 LRCH4 MFSD6 NINJ1 NRM NSG1 NXPE3 ORMDL2 PNLIPRP1 REEP4 SLC10A1 SLC10A6 SLC13A3 SLC22A2 SLC35A4 SLC35B2 SLC38A7 SPP1 STOM TMEM115 TMEM14B TMEM14C TMEM201 TMEM31 TMEM51 TMEM60 TMEM79 TNF TNFRSF10C UBIAD1 VAMP1 VAMP4 VAMP5 VMP1 WFDC2 ZDHHC15
Entrez ID		6843	1727
HPRD ID		01716	08942
Ensembl ID		ENSG00000139190	ENSG00000100243
Uniprot IDs		F5GZV7 P23763	P00387
PDB IDs			1M91 1UMK
Enriched GO Terms of Interacting Partners?
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