STX5 and VCPIP1

Data Source:
HPRD (in vitro, in vivo)

		STX5	VCPIP1
Description		syntaxin 5	valosin containing protein interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Nucleus Cytoplasm Endoplasmic Reticulum Lumen Golgi Stack
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Cadherin Binding Protein N-terminus Binding	Thiol-dependent Ubiquitin-specific Protease Activity Cysteine-type Peptidase Activity
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Fusion Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process COPII Vesicle Coating Vesicle Docking Vesicle Fusion With Golgi Apparatus Golgi Disassembly Regulation Of Golgi Organization	Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Endoplasmic Reticulum Membrane Fusion Protein Ubiquitination Protein Deubiquitination Protein Phosphopantetheinylation Protein K11-linked Deubiquitination Protein K48-linked Deubiquitination Golgi Reassembly Protein-DNA Covalent Cross-linking Repair Regulation Of Protein Localization To Chromatin
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		52 interacting genes: AARD APLP1 AQP6 BAG6 BET1 CCDC153 COPS6 CRB3 CREB3L3 EBP FAM209A GET3 GOSR1 GOSR2 GPANK1 GPR152 HAP1 HSD17B11 HSD17B13 IMMT JAGN1 KASH5 LMNA LNX1 LRIF1 LRRC4C MAGEA6 MTUS1 NAPA NAPB NSFL1C REEP4 RETREG3 SCFD1 SEC22B SNAP23 SNAP25 STING1 STX1A STX2 STX3 STX4 STX8 STXBP1 TACC1 TMEM31 TP53 USO1 VAMP5 VAPB VCP VCPIP1	8 interacting genes: FCHSD2 SMAD9 SNTG2 STX5 UBC VAV2 VCP WAC
Entrez ID		6811	80124
HPRD ID		04426	15645
Ensembl ID		ENSG00000162236	ENSG00000175073
Uniprot IDs		B4DKR0 Q13190	Q96JH7
PDB IDs		3EFO
Enriched GO Terms of Interacting Partners?
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