SRY and ZNF208

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		SRY	ZNF208
Description		sex determining region Y	zinc finger protein 208
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Speck	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Calmodulin Binding Transcription Factor Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Sex Differentiation Anatomical Structure Morphogenesis Positive Regulation Of Gene Expression Cell Differentiation Male Sex Determination Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Male Gonad Development	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Deactivation of the beta-catenin transactivating complex Transcriptional regulation of testis differentiation	Generic Transcription Pathway
Drugs
Diseases		46,XX disorders of sex development (Disorders of gonadal development), including: Ovotesticular DSD; Testicular DSD; Ovarian dysgenesis 46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS			Body mass index (change over time) ( 25378290) Leukocyte telomere length ( 32109421) Systolic blood pressure ( 30578418)
Interacting Genes		7 interacting genes: AR EP300 HDAC3 KPNB1 SLC9A3R2 SMAD3 ZNF208	1 interacting genes: SRY
Entrez ID		6736	7757
HPRD ID		08364	05998
Ensembl ID		ENSG00000184895	ENSG00000160321
Uniprot IDs		A7WPU8 Q05066	M0QYK4 O43345
PDB IDs		1HRY 1HRZ 1J46 1J47 2GZK 6EDB
Enriched GO Terms of Interacting Partners?
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