SRP14 and NSFL1C

Data Source:
HPRD (two hybrid)

		SRP14	NSFL1C
Description		signal recognition particle 14	NSFL1 cofactor
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Secretory Granule Lumen Ficolin-1-rich Granule Lumen	Nucleus Nucleoplasm Chromosome Golgi Stack Cytosol Plasma Membrane Spindle Pole Centrosome Intermediate Filament Cytoskeleton VCP-NSFL1C Complex
	Molecular Function	RNA Binding Protein Binding 7S RNA Binding Endoplasmic Reticulum Signal Peptide Binding	Protein Binding Phospholipid Binding Ubiquitin Binding ATPase Binding
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Neutrophil Degranulation Protein Targeting To ER	Autophagosome Assembly Establishment Of Mitotic Spindle Orientation Golgi Organization Nuclear Envelope Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Centrosome Separation Membrane Fusion Negative Regulation Of Protein Localization To Centrosome
Pathways		SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Neutrophil degranulation
Drugs		Artenimol
Diseases
GWAS		Ewing sarcoma ( 22327514) Obesity-related traits ( 23251661) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		7 interacting genes: CALM1 EAF1 IL7R NSFL1C PTEN SPANXN2 SRP9	16 interacting genes: ANP32A CDK1 DBI FAM32A GLMN GSK3B LIPE NGLY1 PHAX PRKACA RPL22 SRP14 STX5 TARDBP UBC VCP
Entrez ID		6727	55968
HPRD ID		02831	09425
Ensembl ID		ENSG00000140319	ENSG00000088833
Uniprot IDs		P37108	Q53FE8 Q9UNZ2
PDB IDs		1E8O 1E8S 1RY1 4UYJ 4UYK 5AOX	1SS6
Enriched GO Terms of Interacting Partners?
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