NSFL1C and GLMN

Data Source:
HPRD (two hybrid)

		NSFL1C	GLMN
Description		NSFL1 cofactor	glomulin, FKBP associated protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Golgi Stack Cytosol Plasma Membrane Spindle Pole Centrosome Intermediate Filament Cytoskeleton VCP-NSFL1C Complex	Cytoplasm Cullin-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Cul3-RING Ubiquitin Ligase Complex Cul4A-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Phospholipid Binding Ubiquitin Binding ATPase Binding	Signaling Receptor Binding Hepatocyte Growth Factor Receptor Binding Protein Binding Ubiquitin Protein Ligase Binding Ubiquitin-protein Transferase Inhibitor Activity
	Biological Process	Autophagosome Assembly Establishment Of Mitotic Spindle Orientation Golgi Organization Nuclear Envelope Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Centrosome Separation Membrane Fusion Negative Regulation Of Protein Localization To Centrosome	Vasculogenesis Positive Regulation Of Cytokine Production Neural Tube Closure Cell Surface Receptor Signaling Pathway Negative Regulation Of Cell Population Proliferation Negative Regulation Of Protein Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Interleukin-2 Production Regulation Of Gene Expression, Epigenetic Negative Regulation Of T Cell Proliferation Positive Regulation Of Phosphorylation Muscle Cell Differentiation
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases			Venous malformations, including: Sporadic venous malformation; Cutaneomucosal venous malformation; Glomuvenous malformation
GWAS			Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 27863252) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Myeloid white cell count ( 27863252)
Interacting Genes		16 interacting genes: ANP32A CDK1 DBI FAM32A GLMN GSK3B LIPE NGLY1 PHAX PRKACA RPL22 SRP14 STX5 TARDBP UBC VCP	16 interacting genes: BIRC2 BIRC3 EFS FBXW7 FKBP1A FKBP4 FKBP5 HSPB1 MET NSFL1C PEX5 PRDM16 RBX1 RNF7 SKP1 SNAI1
Entrez ID		55968	11146
HPRD ID		09425	03451
Ensembl ID		ENSG00000088833	ENSG00000174842
Uniprot IDs		Q53FE8 Q9UNZ2	B4DJ85 Q92990
PDB IDs		1SS6	4F52
Enriched GO Terms of Interacting Partners?
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