SMARCC1 and MSL1

Data Source:
BioGRID (two hybrid)

		SMARCC1	MSL1
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1	MSL complex subunit 1
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GO Annotations	Cellular Component	Chromatin XY Body Nucleus Nucleoplasm Cytoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Nucleus Nucleoplasm Nuclear Speck MSL Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding Protein N-terminus Binding	Chromatin Binding Protein Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Insulin Receptor Signaling Pathway Animal Organ Morphogenesis Prostate Gland Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Histone H4-K16 Acetylation
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	HATs acetylate histones
Drugs
Diseases
GWAS		Household income (MTAG) ( 31844048) Renal underexcretion gout ( 32238385) Systolic blood pressure ( 31928498)	Asthma ( 31619474)
Interacting Genes		53 interacting genes: ADAMTSL4 ADD1 AKT1 CCNE1 CEBPB CFP CIDEB CYSRT1 EWSR1 FANCA FUS GATA1 GLRX3 GSTO2 ITCH KLF1 KRTAP13-3 KRTAP19-2 KRTAP21-2 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 LRP2BP MGAT5B MSL1 MYC NCOA1 NEDD4 NONO NR3C1 OTX1 PLSCR1 PPIP5K2 PRMT5 PTH1R RELB SIN3A SLC15A2 SMARCA4 SMARCD3 SP1 SPATA12 TAF15 TRIM42 UFSP1 VGLL3 ZNF581	17 interacting genes: CRKL FCHSD2 H2BC21 HORMAD1 HSPB1 KPNB1 MORF4L1 MRGBP NUPR1 PAF1 PPM1G RAN RNF20 RNF40 SMARCC1 SNW1 UBE2D3
Entrez ID		6599	339287
HPRD ID		03435	19425
Ensembl ID		ENSG00000173473	ENSG00000188895
Uniprot IDs		Q58EY4 Q92922	B3KWR7 Q68DK7
PDB IDs		2YUS 5GJK 6KZ7	4B7Y 4B86 4DNC
Enriched GO Terms of Interacting Partners?
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