MSL1 and RNF40

Data Source:
BioGRID (pull down)

		MSL1	RNF40
Description		MSL complex subunit 1	ring finger protein 40
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck MSL Complex	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytosol Membrane Extrinsic Component Of Membrane HULC Complex Neuron Projection Axon Terminus
	Molecular Function	Chromatin Binding Protein Binding	MRNA 3'-UTR Binding Ubiquitin-protein Transferase Activity Protein Binding Syntaxin-1 Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Histone H4-K16 Acetylation	Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Cell Cycle Histone Monoubiquitination Protein Ubiquitination Histone H2B Ubiquitination Response To Peptide Hormone Negative Regulation Of MRNA Polyadenylation Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Polyubiquitination Positive Regulation Of Histone H2B Ubiquitination
Pathways		HATs acetylate histones	E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Asthma ( 31619474)	Immunoglobulin light chain (AL) amyloidosis ( 28025584)
Interacting Genes		17 interacting genes: CRKL FCHSD2 H2BC21 HORMAD1 HSPB1 KPNB1 MORF4L1 MRGBP NUPR1 PAF1 PPM1G RAN RNF20 RNF40 SMARCC1 SNW1 UBE2D3	26 interacting genes: AMOTL2 ATM CCDC146 CDC73 DISC1 DUSP29 EEF1D ITSN1 KIF11 MEOX2 MSL1 MTNR1B NCBP1 NINL RB1 RNF20 SFR1 TRIM51 UBE2A UBE2B UBE2D2 UBE2E1 UBE2I UBE2L6 ZCCHC12 ZNF451
Entrez ID		339287	9810
HPRD ID		19425	07411
Ensembl ID		ENSG00000188895	ENSG00000103549
Uniprot IDs		B3KWR7 Q68DK7	A8K6K1 O75150
PDB IDs		4B7Y 4B86 4DNC
Enriched GO Terms of Interacting Partners?
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