SLC18A3 and PEDS1-UBE2V1

Data Source:
BioGRID (two hybrid)

		SLC18A3	PEDS1-UBE2V1
Description		solute carrier family 18 member A3	PEDS1-UBE2V1 readthrough
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane AP-1 Adaptor Complex AP-2 Adaptor Complex Clathrin-coated Vesicle Membrane Terminal Bouton Clathrin-sculpted Acetylcholine Transport Vesicle Membrane
	Molecular Function	Acetylcholine Transmembrane Transporter Activity Protein Binding Transmembrane Transporter Activity
	Biological Process	Chemical Synaptic Transmission Neurotransmitter Secretion Organic Cation Transport Transmembrane Transport Membrane Organization Acetate Ester Transport
Pathways		Acetylcholine Neurotransmitter Release Cycle Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	NOD1/2 Signaling Pathway TICAM1, RIP1-mediated IKK complex recruitment Downstream TCR signaling FCERI mediated NF-kB activation TAK1 activates NFkB by phosphorylation and activation of IKKs complex activated TAK1 mediates p38 MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 CLEC7A (Dectin-1) signaling Interleukin-1 signaling IRAK1 recruits IKK complex IKK complex recruitment mediated by RIP1 Aggrephagy Aggrephagy TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 31036433)
Interacting Genes		3 interacting genes: CCDC167 MFF PEDS1-UBE2V1	17 interacting genes: AQP6 CNR2 CREB3L1 FAM209A GPR152 PGRMC2 SLC10A1 SLC10A6 SLC18A3 SLC30A4 STOM TMEM31 TMEM52B TMX2 TRAF6 TRHR UBE2N
Entrez ID		6572	387522
HPRD ID		08979	11926
Ensembl ID		ENSG00000187714	ENSG00000124208
Uniprot IDs		Q16572	A5PLL7 Q13404
PDB IDs			2A4D 2C2V 2HLW 6D6I
Enriched GO Terms of Interacting Partners?
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