SLC6A12 and LIN7A

Data Source:
HPRD (in vitro, in vivo)

		SLC6A12	LIN7A
Description		solute carrier family 6 member 12	lin-7 homolog A, crumbs cell polarity complex component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Neuron Projection	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Basolateral Plasma Membrane Synapse Extracellular Exosome MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane
	Molecular Function	Gamma-aminobutyric Acid:sodium Symporter Activity Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity	Protein Binding L27 Domain Binding
	Biological Process	Amino Acid Transmembrane Transport Neurotransmitter Transport Amino Acid Transport Monocarboxylic Acid Transport Gamma-aminobutyric Acid Transport Sodium Ion Transmembrane Transport	Exocytosis Neurotransmitter Secretion Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Synaptic Vesicle Transport Inner Ear Development Protein-containing Complex Assembly Protein Localization To Basolateral Plasma Membrane
Pathways		Amino acid transport across the plasma membrane Na+/Cl- dependent neurotransmitter transporters Creatine metabolism Reuptake of GABA	Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs		Guvacine
Diseases
GWAS		Blood metabolite levels ( 24816252) Chronic kidney disease ( 20383146) Diisocyanate-induced asthma ( 25918132) Metabolite levels ( 23823483 23378610)	Age-related cataracts (age at onset) ( 25352737) Dental caries ( 23259602)
Interacting Genes		4 interacting genes: CD79A ERBIN LIN7A REL	24 interacting genes: ABCA1 ADGRB1 APP BAIAP2 CASK CHRD DLG2 DLG3 DLG4 DNAJC5 ECM1 FAM9B GOLGA2 GRIN2B KCNJ12 MDFI MPP2 MPP3 MPP7 NOTCH2NLA PALS1 PALS2 SLC6A12 ZYX
Entrez ID		6539	8825
HPRD ID		04358	04542
Ensembl ID		ENSG00000111181	ENSG00000111052
Uniprot IDs		P48065	O14910
PDB IDs
Enriched GO Terms of Interacting Partners?
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