SLC2A4 and FAR1

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		SLC2A4	FAR1
Description		solute carrier family 2 member 4	fatty acyl-CoA reductase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Multivesicular Body Trans-Golgi Network Cytosol Plasma Membrane Integral Component Of Plasma Membrane Clathrin-coated Pit External Side Of Plasma Membrane Endomembrane System Vesicle Membrane Membrane Sarcoplasmic Reticulum Clathrin-coated Vesicle Trans-Golgi Network Transport Vesicle T-tubule Cytoplasmic Vesicle Membrane Insulin-responsive Compartment Sarcolemma Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Presynapse	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Peroxisomal Matrix Intracellular Membrane-bounded Organelle
	Molecular Function	Glucose Transmembrane Transporter Activity Protein Binding D-glucose Transmembrane Transporter Activity	Protein Binding Oxidoreductase Activity Fatty-acyl-CoA Reductase (alcohol-forming) Activity Alcohol-forming Fatty Acyl-CoA Reductase Activity
	Biological Process	Carbohydrate Metabolic Process Learning Or Memory Short-term Memory Long-term Memory Amylopectin Biosynthetic Process Positive Regulation Of Brain-derived Neurotrophic Factor Receptor Signaling Pathway Cellular Response To Insulin Stimulus Glucose Homeostasis Glucose Import In Response To Insulin Stimulus Response To Ethanol Glucose Import Brown Fat Cell Differentiation Cellular Response To Tumor Necrosis Factor Cellular Response To Hypoxia Cellular Response To Osmotic Stress Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Transport Across Blood-brain Barrier Glucose Transmembrane Transport	Ether Lipid Biosynthetic Process Wax Biosynthetic Process Long-chain Fatty-acyl-CoA Metabolic Process Glycerophospholipid Biosynthetic Process
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Cellular hexose transport Transcriptional regulation of white adipocyte differentiation	Wax biosynthesis
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Birth weight ( 23202124 31043758) Diastolic blood pressure ( 28135244) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Medication use (diuretics) ( 31015401) Metabolite levels ( 22286219) Offspring birth weight ( 31043758) Pulse pressure ( 28135244) Systolic blood pressure ( 30578418) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Childhood ear infection ( 27182965) Common carotid intima-media thickness in HIV negative individuals ( 29206233) Night sleep phenotypes ( 27126917) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627) Visceral adipose tissue adjusted for BMI ( 26480920)
Interacting Genes		40 interacting genes: ACOX1 ACTN1 ACTN4 AKT2 AP1M1 ARF3 ARFIP1 BSG C1QTNF5 CCDC116 CFL1 CREB3 CTSD DAXX DLD EHD2 ESYT2 FAR1 FKBP10 GAPDH HADH HK2 HSP90AA1 IDH2 KLHL41 LNPEP MAP1S MVP P3H1 P3H4 PDIA6 PRKAR1A PSMD7 RAB7A SERPINH1 SRFBP1 STRN3 UBA52 UBE2I UBE2N	2 interacting genes: ATXN1 SLC2A4
Entrez ID		6517	84188
HPRD ID		00688	14724
Ensembl ID		ENSG00000181856	ENSG00000197601
Uniprot IDs		P14672	Q8WVX9
PDB IDs
Enriched GO Terms of Interacting Partners?
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