SLC1A2 and AJUBA

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		SLC1A2	AJUBA
Description		solute carrier family 1 member 2	ajuba LIM protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Cell Body Membrane Raft Astrocyte Projection Membrane Protein Complex Integral Component Of Presynaptic Membrane	P-body Nucleus Nucleoplasm Transcription Regulator Complex Golgi Apparatus Microtubule Organizing Center Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Focal Adhesion Lamellipodium
	Molecular Function	L-glutamate Transmembrane Transporter Activity High-affinity Glutamate Transmembrane Transporter Activity Protein Binding Glutamate:sodium Symporter Activity Metal Ion Binding	Chromatin Binding Transcription Corepressor Activity Protein Binding Alpha-catenin Binding Metal Ion Binding Actin Filament Binding
	Biological Process	Ion Transport Chemical Synaptic Transmission Glutamate Secretion L-glutamate Transmembrane Transport Protein Homotrimerization Transepithelial Transport L-aspartate Transmembrane Transport D-aspartate Import Across Plasma Membrane L-glutamate Import Across Plasma Membrane Transport Across Blood-brain Barrier	G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Response To Hypoxia Regulation Of Transcription, DNA-templated Cytoskeleton Organization Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Lamellipodium Assembly Regulation Of Cell Migration Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Protein-containing Complex Assembly Negative Regulation Of Kinase Activity Cellular Protein Localization Gene Silencing By MiRNA Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Hippo Signaling Regulation Of GTPase Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAP Kinase Activity Glycerophospholipid Biosynthetic Process Focal Adhesion Assembly Regulation Of Cellular Response To Hypoxia Positive Regulation Of Gene Silencing By MiRNA
Pathways		Astrocytic Glutamate-Glutamine Uptake And Metabolism Glutamate Neurotransmitter Release Cycle Transport of inorganic cations/anions and amino acids/oligopeptides	Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Regulation of PLK1 Activity at G2/M Transition Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs		Glutamic acid
Diseases
GWAS		Autoimmune thyroid disease ( 32581359) Corpus callosum mid-anterior volume ( 31530798) Essential tremor ( 22764253) Health literacy ( 31250787) Lung function (FEV1/FVC) ( 30804560) Medication use (thyroid preparations) ( 31015401) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Psychosis proneness (revised physical anhedonia scale and revised social anhedonia scale) ( 28525603) Relative hand skill in reading disability ( 24068947) Staphylococcus aureus nasal carriage (persistent) ( 26569114) Type 2 diabetes ( 30718926) Vitiligo ( 27723757)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Insular cortex volume ( 31530798) Macular thickness ( 30535121) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Spatial processing ( 31596458)
Interacting Genes		2 interacting genes: AJUBA GRB2	20 interacting genes: ACTA1 AURKAIP1 AURKB BCAR1 CATSPER1 CREB5 CTNNA1 FARS2 GFI1B GRB2 LATS2 LCK LGALS14 PIN1 SLC1A2 TEKT3 TFAP4 TSG101 ZNF512B ZNF541
Entrez ID		6506	84962
HPRD ID		02625	16426
Ensembl ID		ENSG00000110436	ENSG00000129474
Uniprot IDs		A0A2R8Y4W1 A0A2R8Y860 A0A2R8YFE3 A0A2U3TZS7 A2A2U1 P43004	Q96IF1
PDB IDs
Enriched GO Terms of Interacting Partners?
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