NDRG4 and TMEM208

Data Source:
BioGRID (two hybrid)

		NDRG4	TMEM208
Description		NDRG family member 4	transmembrane protein 208
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Endoplasmic Reticulum Membrane Cytosol Basolateral Plasma Membrane Cell Projection Membrane	Vacuole Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Heart Looping Signal Transduction Brain Development Visual Learning Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Negative Regulation Of Smooth Muscle Cell Migration Cell Differentiation Embryonic Heart Tube Development Vesicle Docking Negative Regulation Of Smooth Muscle Cell Proliferation Cardiac Muscle Cell Proliferation Cell Migration Involved In Heart Development Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Endocytic Recycling	Vacuolar Protein Processing Autophagy
Pathways
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 20062063) Oily fish consumption ( 32066663) Pork consumption ( 32066663) QT interval ( 22726844 19305408 19305409) Schizophrenia ( 29483656)
Interacting Genes		36 interacting genes: AGTRAP APLNR ARFIP2 ARL6IP1 ATP5PF CACFD1 CDR1 CIDEB CMTM5 COQ3 CPLX2 DERL3 DGAT2L6 ERGIC3 LEUTX LIME1 LRRC59 MAL2 MTIF3 PLP2 PRAF2 RABAC1 REEP6 RTN3 SCAMP1 SDR16C5 SFT2D2 SGK1 SIN3A SMPD2 SYNGR1 SYNGR3 SYP THAP4 TMEM208 YIF1A	23 interacting genes: C10orf67 CREB3L1 EBP FAM209A GPR152 GPRC5D KCNJ6 LMNA MFSD14B NDRG4 PGRMC2 REEP2 REEP4 RNF19B SCARA5 SCN3B SLC10A6 SLC30A8 SLC7A8 SPG21 STOM TMEM31 TMX2
Entrez ID		65009	29100
HPRD ID		14817	13710
Ensembl ID		ENSG00000103034	ENSG00000168701
Uniprot IDs		A0A024R6V8 A0A0S2Z5L7 A0A0S2Z5R7 B7Z9X4 Q9ULP0	J3KRY7 Q9BTX3
PDB IDs
Enriched GO Terms of Interacting Partners?
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