NDRG4 and SDR16C5

Data Source:
BioGRID (two hybrid)

		NDRG4	SDR16C5
Description		NDRG family member 4	short chain dehydrogenase/reductase family 16C member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Endoplasmic Reticulum Membrane Cytosol Basolateral Plasma Membrane Cell Projection Membrane	Chromatin Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Plasma Membrane Integral Component Of Membrane Transcription Repressor Complex
	Molecular Function	Molecular_function Protein Binding	Transcription Corepressor Activity Retinol Dehydrogenase Activity Protein Binding Transcription Factor Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Activating Transcription Factor Binding
	Biological Process	Heart Looping Signal Transduction Brain Development Visual Learning Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Negative Regulation Of Smooth Muscle Cell Migration Cell Differentiation Embryonic Heart Tube Development Vesicle Docking Negative Regulation Of Smooth Muscle Cell Proliferation Cardiac Muscle Cell Proliferation Cell Migration Involved In Heart Development Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Endocytic Recycling	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Deacetylation Negative Regulation Of Histone Acetylation Retinol Metabolic Process Retinal Metabolic Process Keratinocyte Proliferation
Pathways			RA biosynthesis pathway
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 20062063) Oily fish consumption ( 32066663) Pork consumption ( 32066663) QT interval ( 22726844 19305408 19305409) Schizophrenia ( 29483656)	Depressive symptoms x dependent stressful life events interaction (2df test) ( 30718454) Height ( 28552196 20881960 31562340) Refractive error ( 32231278)
Interacting Genes		36 interacting genes: AGTRAP APLNR ARFIP2 ARL6IP1 ATP5PF CACFD1 CDR1 CIDEB CMTM5 COQ3 CPLX2 DERL3 DGAT2L6 ERGIC3 LEUTX LIME1 LRRC59 MAL2 MTIF3 PLP2 PRAF2 RABAC1 REEP6 RTN3 SCAMP1 SDR16C5 SFT2D2 SGK1 SIN3A SMPD2 SYNGR1 SYNGR3 SYP THAP4 TMEM208 YIF1A	12 interacting genes: EHHADH EXTL1 FUNDC2 GAD2 HSFX1 HSFX2 NDRG4 NLK SENP2 SNX1 SYT16 TTPA
Entrez ID		65009	195814
HPRD ID		14817	12351
Ensembl ID		ENSG00000103034	ENSG00000170786
Uniprot IDs		A0A024R6V8 A0A0S2Z5L7 A0A0S2Z5R7 B7Z9X4 Q9ULP0	B3KT84 G3V145 Q8N3Y7
PDB IDs
Enriched GO Terms of Interacting Partners?
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