AEN and GNPTAB

Data Source:
BioGRID (two hybrid)

		AEN	GNPTAB
Description		apoptosis enhancing nuclease	N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Membrane	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Nucleic Acid Binding Exonuclease Activity Protein Binding	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity Calcium Ion Binding Protein Binding
	Biological Process	Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Nucleic Acid Phosphodiester Bond Hydrolysis	Lysosome Organization N-glycan Processing To Lysosome Secretion Of Lysosomal Enzymes Carbohydrate Phosphorylation
Pathways
Drugs
Diseases			Mucolipidosis II and III, including: Mucolipidosis II / I-cell disease; Mucolipidosis III A / Pseudo-Hurler polydystrophy; Mucolipidosis III C
GWAS		Dupuytren's disease ( 28886342) Night sleep phenotypes ( 27126917)	Blood protein levels ( 29875488 28240269) Bone mineral density (total hip) ( 29883787) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		37 interacting genes: AAMP EMD EXOSC8 GNPTAB HAP1 HOMEZ IKZF1 KANK2 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SPOP SSX2IP TLE5 TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF408 ZNF473	8 interacting genes: AEN APP DISC1 FAM90A1 MAPK1 PSMA1 STAMBPL1 ZNF250
Entrez ID		64782	79158
HPRD ID		08573	11350
Ensembl ID		ENSG00000181026	ENSG00000111670
Uniprot IDs		Q8WTP8	Q3T906
PDB IDs			2N6D
Enriched GO Terms of Interacting Partners?
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