AEN and RALYL

Data Source:
BioGRID (two hybrid)

		AEN	RALYL
Description		apoptosis enhancing nuclease	RALY RNA binding protein like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Membrane	Nucleus Nucleoplasm
	Molecular Function	Nucleic Acid Binding Exonuclease Activity Protein Binding	RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342) Night sleep phenotypes ( 27126917)	Adult body size ( 32376654) Body mass index ( 28892062 25673413) Depressive symptoms x independent stressful life events interaction (1df test) ( 30718454) Depressive symptoms x independent stressful life events interaction (2df test) ( 30718454) Diastolic blood pressure ( 27841878) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Night sleep phenotypes ( 27126917) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Systolic blood pressure ( 27841878) Trunk fat mass ( 28552196)
Interacting Genes		37 interacting genes: AAMP EMD EXOSC8 GNPTAB HAP1 HOMEZ IKZF1 KANK2 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SPOP SSX2IP TLE5 TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF408 ZNF473	22 interacting genes: AEBP2 AEN BYSL C20orf27 CAMK2A CCDC85B CEP170P1 EWSR1 FXR2 HNRNPC HNRNPCL1 HNRNPCL2 LMO3 LRRK2 MCRS1 PSMF1 RALY RBM41 THAP1 TIGD3 TSNAX ZNF408
Entrez ID		64782	138046
HPRD ID		08573	11236
Ensembl ID		ENSG00000181026	ENSG00000184672
Uniprot IDs		Q8WTP8	B3KT61 Q86SE5
PDB IDs
Enriched GO Terms of Interacting Partners?
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