MEAF6 and JADE2

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		MEAF6	JADE2
Description		MYST/Esa1 associated factor 6	jade family PHD finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Nucleolus NuA4 Histone Acetyltransferase Complex MOZ/MORF Histone Acetyltransferase Complex NuA3a Histone Acetyltransferase Complex NuA3b Histone Acetyltransferase Complex	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome
	Molecular Function	Protein Binding Histone Acetyltransferase Activity (H3-K23 Specific)	Protein Binding Transferase Activity Metal Ion Binding
	Biological Process	Histone H2A Acetylation Histone H3-K23 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Histone H3-K14 Acetylation Regulation Of Signal Transduction By P53 Class Mediator	Protein Ubiquitination Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation
Pathways		HATs acetylate histones HATs acetylate histones Regulation of TP53 Activity through Acetylation	HATs acetylate histones
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045)	Adult body size ( 32376654) Age at first birth ( 27798627) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet distribution width ( 27863252) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 28869590) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: C2CD6 CCDC85B FXR2 JADE2 L3MBTL2 LDOC1 MRGBP PLEKHF2 TRIM54	16 interacting genes: CBX8 CDCA7L CSNK2A1 FBXO7 GAS2L2 GORASP2 H3-4 ING4 ING5 MEAF6 PACSIN1 SASH1 ZBTB3 ZBTB5 ZNF417 ZNF496
Entrez ID		64769	23338
HPRD ID		13347	15124
Ensembl ID		ENSG00000163875	ENSG00000043143
Uniprot IDs		Q9HAF1	A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1
PDB IDs
Enriched GO Terms of Interacting Partners?
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