SGCD and FLNC

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SGCD	FLNC
Description		sarcoglycan delta	filamin C
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Integral Component Of Membrane Sarcolemma	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Sarcoplasm Z Disc Sarcolemma Costamere
	Molecular Function		Actin Binding Protein Binding Cytoskeletal Protein Binding Ankyrin Binding
	Biological Process	Muscle Organ Development Cardiac Muscle Tissue Development Heart Contraction	Cell Junction Assembly Muscle Fiber Development
Pathways			Cell-extracellular matrix interactions
Drugs
Diseases		Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD) Dilated cardiomyopathy (DCM)	Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
GWAS		Airway responsiveness in chronic obstructive pulmonary disease ( 25514360) Anthropometric traits ( 19260139) Daytime sleep phenotypes ( 27126917) Egg allergy ( 25710614) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Evening vs. morning chronotype (sMEQ score) ( 32579418) Glycemic traits (pleiotropy) ( 31021400) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HIV-1 viral setpoint ( 26039976) Multiple sclerosis (age of onset) ( 19010793) Obesity-related traits ( 23251661) Pulse pressure ( 30578418) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Resting-state electroencephalogram vigilance ( 29703947) Superior temporal sulcus banks volume ( 31530798) T-Cell Immunoglobulin and Mucin domain 1 levels ( 32460577)	Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		6 interacting genes: ADA FLNC SERPINA3 SGCA SGCB SGCG	35 interacting genes: ADRA1A ADRA1B ADRA1D CAPN3 CDC42 ENO1 FURIN HIPK3 HSPB2 INPPL1 KCND2 KY MAP2K4 MTDH MYBPC2 MYOT MYOZ1 MYOZ2 MYOZ3 NPHP1 PHLDB2 PRKAB2 PRKCA REPS1 RPS6KA2 SGCD SGCG SYNPO2 TRIM54 TRIM55 TRIM63 USP25 WNK1 XIRP1 XIRP2
Entrez ID		6444	2318
HPRD ID		03246	00018
Ensembl ID		ENSG00000170624	ENSG00000128591
Uniprot IDs		Q92629	Q14315 Q59H94
PDB IDs			1V05 2D7M 2D7N 2D7O 2D7P 2D7Q 2K9U 2NQC 3V8O 4MGX
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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