FLNC and MYOZ2

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		FLNC	MYOZ2
Description		filamin C	myozenin 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Sarcoplasm Z Disc Sarcolemma Costamere	Actin Cytoskeleton Sarcomere Z Disc
	Molecular Function	Actin Binding Protein Binding Cytoskeletal Protein Binding Ankyrin Binding	Actin Binding Protein Binding Protein Phosphatase 2B Binding Telethonin Binding FATZ Binding
	Biological Process	Cell Junction Assembly Muscle Fiber Development	Negative Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Biological_process Skeletal Muscle Fiber Adaptation Sarcomere Organization Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		Cell-extracellular matrix interactions
Drugs
Diseases		Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
GWAS		Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)	HDL cholesterol levels ( 32203549) Immature fraction of reticulocytes ( 32888494) PR interval ( 32439900) Refractive error ( 32231278)
Interacting Genes		35 interacting genes: ADRA1A ADRA1B ADRA1D CAPN3 CDC42 ENO1 FURIN HIPK3 HSPB2 INPPL1 KCND2 KY MAP2K4 MTDH MYBPC2 MYOT MYOZ1 MYOZ2 MYOZ3 NPHP1 PHLDB2 PRKAB2 PRKCA REPS1 RPS6KA2 SGCD SGCG SYNPO2 TRIM54 TRIM55 TRIM63 USP25 WNK1 XIRP1 XIRP2	18 interacting genes: ACTN1 ACTN2 ACTN4 CRK DRICH1 EWSR1 FLNC HSPB2 LDB3 MBLAC1 MKRN3 MYB PDLIM3 PPP3CA PPP3CB RBPMS WWOX ZDHHC17
Entrez ID		2318	51778
HPRD ID		00018	05724
Ensembl ID		ENSG00000128591	ENSG00000172399
Uniprot IDs		Q14315 Q59H94	Q9NPC6
PDB IDs		1V05 2D7M 2D7N 2D7O 2D7P 2D7Q 2K9U 2NQC 3V8O 4MGX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?