GMCL1 and PTPN7

Data Source:
BioGRID (two hybrid)

		GMCL1	PTPN7
Description		germ cell-less 1, spermatogenesis associated	protein tyrosine phosphatase non-receptor type 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Matrix	Nucleoplasm Cytoplasm Cytosol Cytoplasmic Side Of Plasma Membrane Microtubule Cytoskeleton Mitotic Spindle
	Molecular Function	Protein Binding Identical Protein Binding	Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Multicellular Organism Development Germ Cell Development Spermatogenesis	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Cellular Response To Cytokine Stimulus
Pathways			Negative regulation of MAPK pathway Interleukin-37 signaling
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818 30061737 29892015) Colorectal or endometrial cancer ( 26621817) Red cell distribution width ( 32888494) Whole brain grey matter density ( 31530798)	Basophil percentage of white cells ( 32888494) Breast cancer ( 23535733) Mean spheric corpuscular volume ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		99 interacting genes: APLF APOL6 AXIN1 BEGAIN BSCL2 BYSL C5orf60 CCDC13 CCDC25 CDC37 CFAP410 CHIC2 CIB3 CLK2 CUL3 EHHADH ELOA EMD EXOC3 FAM167A FAM50B FKBP1B FLYWCH1 FOSL2 FOXR1 FRMD6 GAGE1 GAGE10 GAGE12B GAGE12G GAGE12I GAGE12J GAGE2A GAGE2C GAGE2E GAGE5 GLRX3 GMCL2 GOLGA2 GRAMD1A HYKK IL17F KANK2 KAT5 KIFC3 KPNA2 KRT75 LNX1 MID1 MID2 MINDY1 MORF4L1 MPPE1 MTRR MYLIP MYO5B NEBL NFIL3 NTAQ1 NUMA1 PARD6B PARP16 PAX4 PBXIP1 PIBF1 PIH1D2 PPP1R18 PTPN7 QRICH1 RAD54B RANBP3 RASA1 RNF4 RNMT SHQ1 SLC15A3 SNX20 STK3 SUMO1 SUMO1P1 SYT17 SYT6 TBC1D1 TLK2 TMPO TRIM13 TRIM21 TRIM38 TRIM54 TSG101 TSSC4 UBE2I XAGE2 XAGE3 YY1 ZBTB24 ZMYM2 ZNF23 ZNF250	17 interacting genes: AATK APP CCDC57 EGFR EPHA2 ERBB3 ERBB4 GMCL1 IGF1R MAPK1 MAPK14 MAPK3 PPP1CA PRKACA PTK7 ROR2 SIRPA
Entrez ID		64395	5778
HPRD ID		13587	01480
Ensembl ID		ENSG00000087338	ENSG00000143851
Uniprot IDs		Q53SE7 Q96IK5	A0A024R9A7 B4DZD9 P35236
PDB IDs			1ZC0 2A3K 2GP0 2GPH 2HVL 2QDC 2QDM 2QDP 3D42 3D44 3O4S 3O4T 3O4U
Enriched GO Terms of Interacting Partners?
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