IKZF4 and CSNK1D

Data Source:
BioGRID (two hybrid)

		IKZF4	CSNK1D
Description		IKAROS family zinc finger 4	casein kinase 1 delta
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body Protein-containing Complex	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Spindle Cytosol Spindle Microtubule Plasma Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Ciliary Basal Body Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding BHLH Transcription Factor Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Cadherin Binding Tau-protein Kinase Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein Homooligomerization	G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Phosphorylation Protein Phosphorylation Microtubule Nucleation Golgi Organization Regulation Of G2/M Transition Of Mitotic Cell Cycle Wnt Signaling Pathway Peptidyl-serine Phosphorylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Circadian Regulation Of Gene Expression Protein Localization To Golgi Apparatus Regulation Of Circadian Rhythm COPII Vesicle Coating Spindle Assembly Protein Localization To Cilium Protein Localization To Centrosome Positive Regulation Of Canonical Wnt Signaling Pathway Ciliary Basal Body-plasma Membrane Docking Positive Regulation Of Wnt-mediated Midbrain Dopaminergic Neuron Differentiation Non-motile Cilium Assembly Positive Regulation Of Non-canonical Wnt Signaling Pathway
Pathways			COPII-mediated vesicle transport Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Circadian Clock Anchoring of the basal body to the plasma membrane Major pathway of rRNA processing in the nucleolus and cytosol AURKA Activation by TPX2
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Alopecia areata ( 20596022 25608926) Anorexia nervosa ( 28494655) Asthma ( 21804548 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Autoimmune traits (pleiotropy) ( 30572963) Brain morphology (MOSTest) ( 32665545) Cognitive ability (MTAG) ( 29186694) Cognitive function ( 25644384) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Neutrophil percentage of granulocytes ( 27863252) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Type 1 diabetes ( 21829393 25751624 18198356) Vitiligo ( 27723757 22561518)
Interacting Genes		20 interacting genes: CDC7 CHD4 CSNK1D FHL2 FOXP3 HDAC2 IKZF1 IKZF2 IKZF3 IKZF5 MCRS1 MOB1A MOB3C NFKBIA NRG1 SIN3A SIN3B TCAF1 TCEA2 TXK	41 interacting genes: AKAP9 APP ARFGAP1 ATM BACE1 BRCA1 CCDC14 CDK5 CTNNB1 DRICH1 DVL1 DVL3 EVI5 GJA1 HIF1A IKZF4 JPT2 KDR LURAP1 LZTS2 MAPT PAK5 PER1 PER2 PER3 PPP1R14A PPP5C PSEN2 PTPRD RAB1A SMAD2 SMAD3 SMURF1 SNAPIN SNCA TP53 TRIM3 TRIM9 YWHAZ ZBTB8A ZNF618
Entrez ID		64375	1453
HPRD ID		05874	02920
Ensembl ID		ENSG00000123411	ENSG00000141551
Uniprot IDs		Q9H2S9	P48730
PDB IDs		2MA7	3UYS 3UYT 3UZP 4HGT 4HNF 4KB8 4KBA 4KBC 4KBK 4TN6 4TW9 4TWC 5IH4 5IH5 5IH6 5MQV 5OKT 5W4W 6F1W 6F26 6GZM 6HMP 6HMR 6PXN 6PXO 6PXP 6RCG 6RCH 6RU6 6RU7 6RU8
Enriched GO Terms of Interacting Partners?
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