SRSF7 and PCBP2

Data Source:
HPRD (in vivo, two hybrid)

		SRSF7	PCBP2
Description		serine and arginine rich splicing factor 7	poly(rC) binding protein 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Postsynaptic Density Membrane Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Protein Domain Specific Binding	Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding C-rich Single-stranded DNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Negative Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Leukemia Inhibitory Factor	MRNA Splicing, Via Spliceosome Regulation Of Gene Expression RNA Metabolic Process MRNA Metabolic Process Negative Regulation Of Type I Interferon Production Viral RNA Genome Replication Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Defense Response To Virus Regulation Of RNA Metabolic Process Defense Response To Virus IRES-dependent Viral Translational Initiation
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS			Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 27863252) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		18 interacting genes: CCNL2 CDK19 CDK6 CLK1 CPSF6 DUSP11 FBXO7 LUC7L LUC7L2 NEDD4 NXF1 PCBP2 PRPF38A RNPS1 SDCBP SREK1 SRPK1 SRPK2	28 interacting genes: BARD1 CASK CNBP FLNA FTH1 HMGA1 HMGA2 HNRNPD HNRNPK HNRNPL LINC01554 NKAP PABPC1 PAXIP1 PCBP1 PRPF40A PTBP1 QKI SF3B2 SLU7 SNRPA SRSF3 SRSF7 UBC WDR77 WDR83 YBX1 YBX3
Entrez ID		6432	5094
HPRD ID		08991	03129
Ensembl ID		ENSG00000115875	ENSG00000197111
Uniprot IDs		Q16629	A0A384N6B9 Q15366
PDB IDs		2HVZ	2AXY 2JZX 2P2R 2PQU 2PY9
Enriched GO Terms of Interacting Partners?
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