SRSF7 and CDK19

Data Source:
BioGRID (enzymatic study)
HPRD (in vivo)

		SRSF7	CDK19
Description		serine and arginine rich splicing factor 7	cyclin dependent kinase 19
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Extracellular Exosome	Nucleus Cytosol Mediator Complex
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Protein Domain Specific Binding	Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Negative Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Leukemia Inhibitory Factor	Protein Phosphorylation Positive Regulation Of Apoptotic Process Positive Regulation Of Inflammatory Response Regulation Of Cell Cycle Cellular Response To Lipopolysaccharide
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			General risk tolerance (MTAG) ( 30643258) Zinc levels ( 26025379)
Interacting Genes		18 interacting genes: CCNL2 CDK19 CDK6 CLK1 CPSF6 DUSP11 FBXO7 LUC7L LUC7L2 NEDD4 NXF1 PCBP2 PRPF38A RNPS1 SDCBP SREK1 SRPK1 SRPK2	7 interacting genes: BCL6 EIF3F PRMT5 SMARCA4 SRSF7 SUZ12 WDR77
Entrez ID		6432	23097
HPRD ID		08991	07627
Ensembl ID		ENSG00000115875	ENSG00000155111
Uniprot IDs		Q16629	B4DUB1 I6W807 Q9BWU1
PDB IDs		2HVZ
Enriched GO Terms of Interacting Partners?
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