SRSF4 and PNN

Data Source:
HPRD (two hybrid, in vivo)

		SRSF4	PNN
Description		serine and arginine rich splicing factor 4	pinin, desmosome associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Intermediate Filament Plasma Membrane Cell-cell Junction Membrane Nuclear Speck Desmosome Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding Sequence-specific MRNA Binding	DNA Binding RNA Binding Structural Molecule Activity Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Response To Insulin Negative Regulation Of MRNA Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome Cell Adhesion
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Artenimol
Diseases
GWAS		Carotid plaque maximum area ( 32469969) Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean area of carotid plaque ( 32469969) Schizophrenia ( 26531332) Tourette syndrome ( 30818990)
Interacting Genes		24 interacting genes: DYRK1A FUS GEMIN2 HAP1 HTATSF1 PNN PPARGC1A PRPF38A RNPS1 SART1 SCAF11 SMURF1 SMURF2 SREK1 SRPK1 SRRM2 SRSF1 SRSF10 SRSF2 SRSF6 TICAM1 TRA2B UBE2I ZDHHC17	18 interacting genes: CNGB1 CSNK2A1 CTBP1 CTBP2 DYNC1I2 KRT18 KRT19 KRT27 KRT8 PNISR PPIG PRPF4B RNPS1 SRPK2 SRRM2 SRSF4 YWHAG ZCCHC17
Entrez ID		6429	5411
HPRD ID		09052	04401
Ensembl ID		ENSG00000116350	ENSG00000100941
Uniprot IDs		Q08170	Q9H307
PDB IDs
Enriched GO Terms of Interacting Partners?
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