PNN and DYNC1I2

Data Source:
HPRD (two hybrid)

		PNN	DYNC1I2
Description		pinin, desmosome associated protein	dynein cytoplasmic 1 intermediate chain 2
Image		No pdb structure
GO Annotations	Cellular Component	Intermediate Filament Plasma Membrane Cell-cell Junction Membrane Nuclear Speck Desmosome Exon-exon Junction Complex Catalytic Step 2 Spliceosome	Cytoplasm Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle
	Molecular Function	DNA Binding RNA Binding Structural Molecule Activity Protein Binding	Microtubule Motor Activity Protein Binding Dynein Light Chain Binding Dynein Heavy Chain Binding
	Biological Process	MRNA Splicing, Via Spliceosome Cell Adhesion	G2/M Transition Of Mitotic Cell Cycle Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Microtubule-based Movement Regulation Of G2/M Transition Of Mitotic Cell Cycle Transport Along Microtubule Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Ciliary Basal Body-plasma Membrane Docking
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase AURKA Activation by TPX2 HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Hippocampal volume ( 25625606) Metabolite levels ( 23823483) Refractive error ( 32231278) Weight ( 28552196)
Interacting Genes		18 interacting genes: CNGB1 CSNK2A1 CTBP1 CTBP2 DYNC1I2 KRT18 KRT19 KRT27 KRT8 PNISR PPIG PRPF4B RNPS1 SRPK2 SRRM2 SRSF4 YWHAG ZCCHC17	8 interacting genes: CCDC136 DCTN1 DYNLRB1 DYNLT1 DYNLT3 NECAB2 PNN PPFIA1
Entrez ID		5411	1781
HPRD ID		04401	04512
Ensembl ID		ENSG00000100941	ENSG00000077380
Uniprot IDs		Q9H307	A0A140VKE9 B4DPZ3 Q13409
PDB IDs			5JPW 6F1T 6F1U 6F1Z 6F38 6F3A
Enriched GO Terms of Interacting Partners?
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