MOAP1 and PPP2R3C

Data Source:
BioGRID (two hybrid)

		MOAP1	PPP2R3C
Description		modulator of apoptosis 1	protein phosphatase 2 regulatory subunit B''gamma
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol	Nucleoplasm Golgi Apparatus Centrosome Spindle Cytosol
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding Metal Ion Binding
	Biological Process	Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Microtubule Cytoskeleton Organization B Cell Homeostasis Regulation Of Antimicrobial Humoral Response Cortical Cytoskeleton Organization Activation Of Protein Kinase Activity Regulation Of Dephosphorylation T Cell Homeostasis Positive Regulation Of B Cell Differentiation Spleen Development Regulation Of Mitochondrial Depolarization
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Endometriosis ( 23472165) Migraine ( 27182965)	Atopic dermatitis ( 26482879) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Colorectal carcinoma in primary sclerosing cholangitis ( 28779025) Lymphocyte counts ( 32888494 27863252) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		23 interacting genes: BAX BCL2 BCL2L1 CACNA1A CAMK2D CCDC85B DPPA2 FZR1 LATS1 MAGEH1 MBIP MEOX2 PNMA5 PPP2R3C RASSF1 RUSC1 THOC1 TNFRSF10A TNFRSF1A UBQLN2 UBQLN4 UBR5 ZMYND12	15 interacting genes: CCDC146 CCDC33 CMTM5 ENKD1 FAM161A FAM161B HSPB1 IKBKB MOAP1 MTNR1A POLR1C PRPF31 RTN3 SMG9 TRIM14
Entrez ID		64112	55012
HPRD ID		17580	12622
Ensembl ID		ENSG00000165943	ENSG00000092020
Uniprot IDs		Q96BY2	Q969Q6
PDB IDs
Enriched GO Terms of Interacting Partners?
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