PERP and ABHD16A

Data Source:
BioGRID (two hybrid)

		PERP	ABHD16A
Description		p53 apoptosis effector related to PMP22	abhydrolase domain containing 16A, phospholipase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Desmosome	Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Phospholipase Activity Lysophospholipase Activity Protein Binding Palmitoyl-(protein) Hydrolase Activity Acylglycerol Lipase Activity
	Biological Process	Desmosome Organization Notch Signaling Pathway Heterotypic Cell-cell Adhesion Regulation Of Apoptotic Process Positive Regulation Of Proteolysis Cornification Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Amelogenesis Activation Of Cysteine-type Endopeptidase Activity Cell-cell Adhesion	Phosphatidylserine Catabolic Process Protein Phosphopantetheinylation Monoacylglycerol Catabolic Process Macromolecule Depalmitoylation Prostaglandin Catabolic Process
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain Formation of the cornified envelope
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Bulimia nervosa ( 23568457) Systemic lupus erythematosus ( 26663301)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Monocyte percentage of white cells ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		2 interacting genes: ABHD16A MAL	69 interacting genes: AGPAT3 AQP6 AQP7 ATP5MC3 ATP5PF BRI3 CBARP CIDEB CREB3 CYP1A2 DNAJC1 DTX2 EBP ERGIC3 FDPS FKBP7 GDAP1 GJA5 GOLT1A GORAB GPR152 GPRC5C GYPC HM13 HNRNPA1 HSD17B13 IFITM1 IFITM3 ITGAM LTA MLH1 MT-ND3 MT-ND4 PERP PILRB PKMYT1 POLE PRAF2 PTGS2 RETREG3 RHBDD2 RHBDL1 RNF5 SAFB SEC22B SERF1A SERF1B SLC10A1 SLC30A2 SLC7A8 SPAG4 SPAG7 STMN4 STX1B TM4SF19 TMEM139 TMEM143 TMEM147 TMEM14B TMEM222 TMEM237 TMEM31 TMEM65 TSPAN2 UNC93A UPF1 VAMP5 VMA21 WBP1L
Entrez ID		64065	7920
HPRD ID		17836	15929
Ensembl ID		ENSG00000112378	ENSG00000204427
Uniprot IDs		Q96FX8	A0A1U9X777 B3KNX9 O95870
PDB IDs
Enriched GO Terms of Interacting Partners?
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