SELP and CD24

Data Source:
BioGRID (pull down)

		SELP	CD24
Description		selectin P	CD24 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Platelet Dense Granule Membrane Platelet Alpha Granule Membrane	Cell Surface Membrane Anchored Component Of External Side Of Plasma Membrane Membrane Raft
	Molecular Function	Lipopolysaccharide Binding Calcium Ion Binding Protein Binding Heparin Binding Sialic Acid Binding Fucose Binding Glycosphingolipid Binding Calcium-dependent Protein Binding Oligosaccharide Binding	Protein Binding Protein Kinase Binding Protein Tyrosine Kinase Activator Activity
	Biological Process	Platelet Degranulation Positive Regulation Of Leukocyte Migration Inflammatory Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Positive Regulation Of Platelet Activation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Response To Lipopolysaccharide Regulation Of Integrin Activation Calcium-mediated Signaling Using Intracellular Calcium Source Defense Response To Gram-negative Bacterium Leukocyte Migration Leukocyte Tethering Or Rolling Positive Regulation Of Leukocyte Tethering Or Rolling	Response To Hypoxia Cell Activation Regulation Of Cytokine-mediated Signaling Pathway Response To Molecule Of Bacterial Origin Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Wnt Signaling Pathway Cell Migration Regulation Of Epithelial Cell Differentiation T Cell Costimulation B Cell Receptor Transport Into Membrane Raft Chemokine Receptor Transport Out Of Membrane Raft Negative Regulation Of Transforming Growth Factor Beta3 Production Positive Regulation Of Activated T Cell Proliferation Regulation Of Phosphorylation Cholesterol Homeostasis Positive Regulation Of MAP Kinase Activity Regulation Of MAPK Cascade Response To Estrogen Respiratory Burst Positive Regulation Of Protein Tyrosine Kinase Activity Glomerular Visceral Epithelial Cell Differentiation Glomerular Parietal Epithelial Cell Differentiation Intrinsic Apoptotic Signaling Pathway Cell-cell Adhesion Positive Regulation Of Nephron Tubule Epithelial Cell Differentiation
Pathways		Platelet degranulation Cell surface interactions at the vascular wall	L1CAM interactions
Drugs		Heparin N-acetyl-alpha-neuraminic acid Dalteparin Nadroparin Crizanlizumab
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Blood protein levels ( 30072576 29875488 28240269) Hippocampal atrophy ( 22745009) Inflammatory bowel disease ( 26192919) L-selectin levels ( 25576479) Late-onset Alzheimer's disease ( 27770636) Optic disc size ( 31809533) Soluble levels of adhesion molecules ( 20167578) Total ventricular volume ( 21116278)
Interacting Genes		10 interacting genes: AP1M1 CD24 EZR FUT4 GP1BA SELPLG SERPING1 SNX17 SNX27 VCAN	2 interacting genes: NPM1 SELP
Entrez ID		6403	100133941
HPRD ID		01433
Ensembl ID		ENSG00000174175	ENSG00000272398
Uniprot IDs		A0A024R8Y9 P16109 Q5R341 Q6NUL9	P25063
PDB IDs		1FSB 1G1Q 1G1R 1G1S 1HES 1KJD
Enriched GO Terms of Interacting Partners?
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