FIGNL1 and SPIDR

Data Source:
BioGRID (pull down)

		FIGNL1	SPIDR
Description		fidgetin like 1	scaffold protein involved in DNA repair
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Nucleus Cytoplasm Perinuclear Region Of Cytoplasm Extracellular Exosome	Nuclear Chromosome Nucleoplasm
	Molecular Function	Magnesium Ion Binding Protein Binding ATP Binding Microtubule-severing ATPase Activity Hydrolase Activity ATPase Activity	Protein Binding
	Biological Process	Osteoblast Differentiation Male Meiotic Nuclear Division Regulation Of Double-strand Break Repair Via Homologous Recombination Cytoplasmic Microtubule Organization Osteoblast Proliferation Negative Regulation Of Apoptotic Process ATP Metabolic Process Microtubule Severing Regulation Of Cell Cycle Cellular Response To Ionizing Radiation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Double-strand Break Repair Via Homologous Recombination Cellular Response To DNA Damage Stimulus Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Protein-containing Complex Assembly Regulation Of Establishment Of Protein Localization To Chromosome Cellular Response To Ionizing Radiation Cellular Response To Hydroxyurea Cellular Response To Camptothecin Positive Regulation Of Double-strand Break Repair
Pathways			Resolution of D-loop Structures through Holliday Junction Intermediates
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Crohn's disease ( 21102463)	Heel bone mineral density ( 30598549) Monocyte percentage of white cells ( 32888494)
Interacting Genes		8 interacting genes: C1orf112 DMC1 GCC1 IDH1 ITGB1BP1 KDM1A RAD51 SPIDR	2 interacting genes: BLM FIGNL1
Entrez ID		63979	23514
HPRD ID		10958	19305
Ensembl ID		ENSG00000132436	ENSG00000164808
Uniprot IDs		B3KNH6 Q6PIW4	Q14159
PDB IDs		3D8B
Enriched GO Terms of Interacting Partners?
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