SEC14L1 and EPB41

Data Source:
HPRD (two hybrid)

		SEC14L1	EPB41
Description		SEC14 like lipid binding 1	erythrocyte membrane protein band 4.1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol	Cytosol Cytoskeleton Plasma Membrane Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Spectrin-associated Cytoskeleton Basolateral Plasma Membrane Nuclear Body Cell Junction Cortical Cytoskeleton Protein-containing Complex Intercellular Bridge Mitotic Spindle Cell Cortex Region
	Molecular Function	Protein Binding RIG-I Binding	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Calmodulin Binding 1-phosphatidylinositol Binding Protein C-terminus Binding Spectrin Binding Protein N-terminus Binding Phosphoprotein Binding
	Biological Process	Choline Transport Negative Regulation Of RIG-I Signaling Pathway Innate Immune Response	Cell Cycle Regulation Of Cell Shape Actin Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Actomyosin Structure Organization Positive Regulation Of Protein Binding Cell Division Regulation Of Calcium Ion Transport Protein-containing Complex Assembly Regulation Of Intestinal Absorption Positive Regulation Of Protein Localization To Cell Cortex
Pathways			Neurexins and neuroligins
Drugs
Diseases			Hereditary elliptocytosis (HE)
GWAS		Cognitive performance ( 19734545) Intraocular pressure ( 30591961) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Tourette syndrome ( 30818990)
Interacting Genes		2 interacting genes: CEP70 EPB41	39 interacting genes: ACTA1 APP BCAM C2CD2L CASK CD44 CENPJ CLNS1A CRYAB DLG1 DRD2 DRD3 EGFR EIF3G EPB42 FKBP2 GDI1 GYPC KPNA2 MACROD1 MYL1 NPPA NUMA1 PRKCB RWDD2B SEC14L1 SLC4A1 SMAD3 SPTAN1 SPTB SPTBN1 TJP2 TPM1 TUBA4A U2AF1 U2AF2 YWHAB YWHAQ ZCCHC10
Entrez ID		6397	2035
HPRD ID		03295	00558
Ensembl ID		ENSG00000129657	ENSG00000159023
Uniprot IDs		A0A024R8V1 A5PLM6 Q59HE8 Q7Z3R7 Q92503	A0A2R8Y7Y3 P11171 Q1WWM3 Q29RX4 Q59F12
PDB IDs			1GG3 2RQ1 3QIJ
Enriched GO Terms of Interacting Partners?
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