CXCL11 and CXCL14

Data Source:
BioGRID (pull down)

		CXCL11	CXCL14
Description		C-X-C motif chemokine ligand 11	C-X-C motif chemokine ligand 14
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Space Golgi Apparatus
	Molecular Function	Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding	Protein Binding Chemokine Activity
	Biological Process	Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Neutrophil Chemotaxis Regulation Of Cell Population Proliferation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide	Chemotaxis Signal Transduction Cell-cell Signaling Negative Regulation Of Myoblast Differentiation Inner Ear Development Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of Natural Killer Cell Chemotaxis
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)	Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Cerebrospinal fluid p-tau levels in Alzheimer's disease dementia ( 29274321) Cerebrospinal fluid t-tau levels ( 29274321)
Interacting Genes		25 interacting genes: CCL1 CCL11 CCL13 CCL20 CCL21 CCL24 CCL25 CCL26 CCL5 CCL8 CCR3 CXCL10 CXCL12 CXCL14 CXCL2 CXCL9 CXCR3 DPP4 LRRK2 MTUS2 PF4 PF4V1 PPBP SMARCB1 XCL1	28 interacting genes: APP CCL11 CCL13 CCL21 CCL26 CCL28 CCL5 CXCL10 CXCL11 CXCL12 CXCL17 CXCL2 CXCL5 CXCL9 F2R GPR85 JMJD6 KLRC1 LMNA PF4 PPBP REL ROBO3 SLAMF6 TEX11 TNFRSF10C TRIM23 XCL1
Entrez ID		6373	9547
HPRD ID		05329	16049
Ensembl ID		ENSG00000169248	ENSG00000145824
Uniprot IDs		O14625	O95715
PDB IDs		1RJT	2HDL
Enriched GO Terms of Interacting Partners?
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