CXCL14 and CXCL10

Data Source:
BioGRID (pull down)

		CXCL14	CXCL10
Description		C-X-C motif chemokine ligand 14	C-X-C motif chemokine ligand 10
Image
GO Annotations	Cellular Component	Extracellular Space Golgi Apparatus	Extracellular Region Extracellular Space External Side Of Plasma Membrane
	Molecular Function	Protein Binding Chemokine Activity	Signaling Receptor Binding Protein Binding Chemokine Activity Heparin Binding CAMP-dependent Protein Kinase Regulator Activity Chemoattractant Activity CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding
	Biological Process	Chemotaxis Signal Transduction Cell-cell Signaling Negative Regulation Of Myoblast Differentiation Inner Ear Development Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of Natural Killer Cell Chemotaxis	Chemotaxis Inflammatory Response Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Muscle Organ Development Blood Circulation Positive Regulation Of Cell Population Proliferation Response To Cold Response To Gamma Radiation T Cell Chemotaxis Regulation Of T Cell Chemotaxis Response To Auditory Stimulus Negative Regulation Of Angiogenesis Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Response To Vitamin D Cellular Response To Heat Endothelial Cell Activation Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Negative Regulation Of Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Chemotaxis Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Positive Regulation Of Monocyte Chemotaxis Regulation Of Endothelial Tube Morphogenesis Negative Regulation Of Myoblast Fusion Positive Regulation Of T Cell Migration Regulation Of CAMP-dependent Protein Kinase Activity
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling
Drugs			N-Methylleucine Eldelumab Clove oil
Diseases
GWAS		Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Cerebrospinal fluid p-tau levels in Alzheimer's disease dementia ( 29274321) Cerebrospinal fluid t-tau levels ( 29274321)	Blood protein levels ( 30072576 29875488 28240269) C-X-C motif chemokine 10 levels ( 25147954) Hippocampal volume ( 29274321) Interferon gamma-induced protein 10 levels ( 27989323 31217265) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
Interacting Genes		28 interacting genes: APP CCL11 CCL13 CCL21 CCL26 CCL28 CCL5 CXCL10 CXCL11 CXCL12 CXCL17 CXCL2 CXCL5 CXCL9 F2R GPR85 JMJD6 KLRC1 LMNA PF4 PPBP REL ROBO3 SLAMF6 TEX11 TNFRSF10C TRIM23 XCL1	22 interacting genes: CCL11 CCL13 CCL21 CCL26 CCL28 CCL5 CCL8 CCR3 CXCL11 CXCL12 CXCL14 CXCL17 CXCL6 CXCL9 CXCR3 DPP4 IGFBP7 PF4 PF4V1 PPBP VCAN XCL1
Entrez ID		9547	3627
HPRD ID		16049	00930
Ensembl ID		ENSG00000145824	ENSG00000169245
Uniprot IDs		O95715	P02778
PDB IDs		2HDL	1LV9 1O7Y 1O7Z 1O80
Enriched GO Terms of Interacting Partners?
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