CCL20 and CXCL11

Data Source:
BioGRID (pull down)

		CCL20	CXCL11
Description		C-C motif chemokine ligand 20	C-X-C motif chemokine ligand 11
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Chemokine Activity CCR6 Chemokine Receptor Binding CCR Chemokine Receptor Binding	Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding
	Biological Process	Monocyte Chemotaxis Chemotaxis Inflammatory Response Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Calcium-mediated Signaling Using Intracellular Calcium Source Defense Response To Bacterium Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Cell Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor T Cell Migration Thymocyte Migration Positive Regulation Of T Cell Migration	Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Neutrophil Chemotaxis Regulation Of Cell Population Proliferation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 31959851 30929738 32296059) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Blood pressure ( 17903302) Crohn's disease ( 26192919) Eating disorders (purging via substances) ( 23568457) Inflammatory bowel disease ( 26192919) Primary biliary cholangitis ( 26394269) Ulcerative colitis ( 26192919)	Blood protein levels ( 30072576 29875488 28240269) Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
Interacting Genes		11 interacting genes: CCL5 CCR6 CXCL11 CXCL12 CXCL17 CXCL5 MTDH PF4 TGFB3 VCAN XCL2	25 interacting genes: CCL1 CCL11 CCL13 CCL20 CCL21 CCL24 CCL25 CCL26 CCL5 CCL8 CCR3 CXCL10 CXCL12 CXCL14 CXCL2 CXCL9 CXCR3 DPP4 LRRK2 MTUS2 PF4 PF4V1 PPBP SMARCB1 XCL1
Entrez ID		6364	6373
HPRD ID		03571	05329
Ensembl ID		ENSG00000115009	ENSG00000169248
Uniprot IDs		P78556	O14625
PDB IDs		1M8A 2HCI 2JYO 5UR7 6WWZ	1RJT
Enriched GO Terms of Interacting Partners?
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