SAFB and TJP2

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		SAFB	TJP2
Description		scaffold attachment factor B	tight junction protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Midbody	Nucleus Nucleoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Cell-cell Contact Zone
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Binding Double-stranded DNA Binding RNA Binding Protein Binding Sequence-specific DNA Binding	Guanylate Kinase Activity Protein Binding Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Cadherin Binding Cell Adhesion Molecule Binding Protein Tyrosine Kinase Binding
	Biological Process	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Intracellular Estrogen Receptor Signaling Pathway Regulation Of MRNA Processing	Homotypic Cell-cell Adhesion Hippo Signaling Maintenance Of Blood-brain Barrier Cell-cell Junction Organization GMP Metabolic Process GDP Metabolic Process Intestinal Absorption Establishment Of Endothelial Intestinal Barrier Regulation Of Membrane Permeability Cell-cell Adhesion Protein Localization To Cell-cell Junction Positive Regulation Of Blood-brain Barrier Permeability
Pathways		SUMOylation of transcription cofactors	Signaling by Hippo Apoptotic cleavage of cell adhesion proteins
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494)	Macular thickness ( 30535121) Myopia ( 27182965) Night sleep phenotypes ( 27126917) Refractive error ( 23396134 32231278) Renal sinus fat ( 22044751) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Weight gain in amisulpride-treated first-episode psychosis ( 32126890)
Interacting Genes		28 interacting genes: ABHD16A CDC37 CHD1 CHD3 CLK1 CSNK2A1 CYCS ESR1 HNRNPA1 HNRNPD HNRNPK IL7R MIR199A1 MIR363 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7D NCOR1 POLR2A SAFB2 SREK1 SRPK1 SRPK2 SRSF9 SUMO2 TAF15 TJP2	17 interacting genes: CDK6 CGN CLDN1 CLDN2 CLK1 CTNNA1 EPB41 HGS HSPB1 SAFB SCRIB SH3KBP1 SRPK2 TJP1 YWHAB YWHAG YWHAZ
Entrez ID		6294	9414
HPRD ID		04205	06369
Ensembl ID		ENSG00000160633	ENSG00000119139
Uniprot IDs		B7Z2F6 B7ZLP5 Q15424	B7Z2R3 B7Z954 Q9UDY2
PDB IDs			2OSG 3E17
Enriched GO Terms of Interacting Partners?
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