SAFB and TAF15

Data Source:
HPRD (in vitro, in vivo)

		SAFB	TAF15
Description		scaffold attachment factor B	TATA-box binding protein associated factor 15
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Midbody	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Binding Double-stranded DNA Binding RNA Binding Protein Binding Sequence-specific DNA Binding	DNA Binding Transcription Coregulator Activity RNA Binding Protein Binding Metal Ion Binding
	Biological Process	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Intracellular Estrogen Receptor Signaling Pathway Regulation Of MRNA Processing	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated MRNA Stabilization Regulation Of Signal Transduction By P53 Class Mediator
Pathways		SUMOylation of transcription cofactors	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases			Extraskeletal myxoid chondrosarcoma
GWAS		Mean reticulocyte volume ( 32888494)	Blood protein levels ( 28240269) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		28 interacting genes: ABHD16A CDC37 CHD1 CHD3 CLK1 CSNK2A1 CYCS ESR1 HNRNPA1 HNRNPD HNRNPK IL7R MIR199A1 MIR363 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7D NCOR1 POLR2A SAFB2 SREK1 SRPK1 SRPK2 SRSF9 SUMO2 TAF15 TJP2	93 interacting genes: ARID1A CACNA1A H2AC20 H3-4 H3C1 H4C14 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I POLR2C POLR2E POLR2G SAFB SF1 SMARCA4 SMARCC1 SMARCC2 TAF1 TAF12 TAF13 TAF5 TAF7 YWHAG ZNF384
Entrez ID		6294	8148
HPRD ID		04205	09031
Ensembl ID		ENSG00000160633	ENSG00000270647
Uniprot IDs		B7Z2F6 B7ZLP5 Q15424	Q92804
PDB IDs			2MMY
Enriched GO Terms of Interacting Partners?
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