RXRG and CKMT1A

Data Source:
BioGRID (two hybrid)

		RXRG	CKMT1A
Description		retinoid X receptor gamma	creatine kinase, mitochondrial 1A
Image
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytoplasm RNA Polymerase II Transcription Regulator Complex	Mitochondrion Mitochondrial Inner Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Retinoic Acid-responsive Element Binding Sequence-specific Double-stranded DNA Binding	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation Response To Retinoic Acid Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Anatomical Structure Development	Creatine Metabolic Process Phosphorylation Phosphocreatine Biosynthetic Process
Pathways		Nuclear Receptor transcription pathway Signaling by Retinoic Acid	Creatine metabolism
Drugs		Adapalene Bexarotene Rosiglitazone Acitretin Alitretinoin Tretinoin Etretinate Bezafibrate Phthalic Acid Doconexent	Creatine Phosphocreatine
Diseases
GWAS		AIDS ( 19754311) Bipolar disorder (age of onset <21) or attention deficit hyperactivity disorder ( 27890468) Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Macular thickness ( 30535121) Menarche (age at onset) ( 27182965 21102462 29773799 25231870) Metabolite levels ( 23823483) Personality traits in bipolar disorder ( 21368711) Proportion of activated microglia (midfrontal cortex) ( 30679421)	Diastolic blood pressure ( 27841878)
Interacting Genes		32 interacting genes: CAMK2B CEBPZ CHGB CKMT1A CKMT1B CREBBP DCK HOXD4 ITGB3BP LRSAM1 MAP4 MPPED2 NCOA6 NCOR2 NR0B2 NR1H2 NR1H3 NR1H4 NR1I2 NR4A1 PICK1 PNO1 PPARA PPARD PPARG RARA RARB RARG SRF THRA THRB VDR	10 interacting genes: ASB9 CKM CTNNA3 HPCA NUTF2 OCM PPP1R16A PSMC3 RXRG VDAC1
Entrez ID		6258	548596
HPRD ID		01579	18683
Ensembl ID		ENSG00000143171	ENSG00000223572
Uniprot IDs		A0A087WZ88 F1D8Q7 F1T097 P48443	P12532
PDB IDs		2GL8 7A79	1QK1
Enriched GO Terms of Interacting Partners?
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