RPS6KB2 and EEF2K

Data Source:
HPRD (in vitro)

		RPS6KB2	EEF2K
Description		ribosomal protein S6 kinase B2	eukaryotic elongation factor 2 kinase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Cytoplasm Cytosol Postsynaptic Density Dendritic Spine
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Ribosomal Protein S6 Kinase Activity ATP Binding Peptide Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Kinase Activity Elongation Factor-2 Kinase Activity Calcium Ion Binding Calmodulin Binding ATP Binding Translation Factor Activity, RNA Binding
	Biological Process	Translation Signal Transduction Peptidyl-serine Phosphorylation TOR Signaling Protein Kinase B Signaling Positive Regulation Of Translational Initiation	Response To Ischemia Translational Elongation Regulation Of Protein Autophosphorylation Cellular Response To Insulin Stimulus Negative Regulation Of Apoptotic Process Positive Regulation Of Endocytosis Protein Autophosphorylation Positive Regulation Of Synapse Assembly Positive Regulation Of Dendritic Spine Morphogenesis Cellular Response To Calcium Ion Cellular Response To CAMP Cellular Response To Anoxia Cellular Response To Brain-derived Neurotrophic Factor Stimulus Response To Prolactin
Pathways		AKT phosphorylates targets in the nucleus Constitutive Signaling by AKT1 E17K in Cancer	mTORC1-mediated signalling
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Refractive error ( 32231278)	Heel bone mineral density ( 30598549)
Interacting Genes		22 interacting genes: BTK COASY CSNK2B EEF2K EP300 FBXO25 FYN HNRNPA1 IKBKG KAT2B LRRK2 LYN MAPK8IP2 MTOR NEDD4L PDGFRB PDPK1 PRKCE RPS6 SRC SRPK1 SYK	17 interacting genes: CDK1 EEF2 MAPK11 MAPK12 MAPK13 MAPK14 MAPK8 MAPK9 MAPKAPK2 MAPKAPK3 MAPKAPK5 PRKAA1 PRKAA2 PRKACA RPS6KA1 RPS6KB1 RPS6KB2
Entrez ID		6199	29904
HPRD ID		10203	07369
Ensembl ID		ENSG00000175634	ENSG00000103319
Uniprot IDs		Q9UBS0	O00418
PDB IDs			5J8H 5KS5 6NX4
Enriched GO Terms of Interacting Partners?
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