RPL6 and MT-ND1

Data Source:
BioGRID (two hybrid)

		RPL6	MT-ND1
Description		ribosomal protein L6	NADH dehydrogenase subunit 1
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GO Annotations	Cellular Component	Nucleus Rough Endoplasmic Reticulum Cytosol Focal Adhesion Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Cytoplasmic Ribonucleoprotein Granule Polysomal Ribosome	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Integral Component Of Membrane Dendrite Mitochondrial Membrane Neuronal Cell Body
	Molecular Function	DNA Binding RNA Binding Structural Constituent Of Ribosome Protein Binding Cadherin Binding	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Ribosomal Large Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Regulation Of Transcription, DNA-templated Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Response To Organic Cyclic Compound Mitochondrial Respiratory Chain Complex I Assembly Response To Hydroperoxide Response To Drug
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Respiratory electron transport Complex I biogenesis
Drugs			NADH Methoxyflurane Halothane Desflurane Sevoflurane N-Formylmethionine Phenethyl Isothiocyanate
Diseases			Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS		Blond vs. brown/black hair color ( 30531825) Blood pressure ( 21572416) Body mass index ( 26426971) Coffee consumption ( 29367735) Diastolic blood pressure ( 26390057) Esophageal cancer ( 21642993) Systolic blood pressure ( 26390057)
Interacting Genes		16 interacting genes: CSNK2A1 DUX4 EIF6 FBXO7 FGF2 H2AC4 IL7R IVNS1ABP LINC01554 MAP3K14 MT-ND1 NFKB2 NPAS2 RPL29 SEL1L STAU1	12 interacting genes: BARD1 BRCA1 DHDDS FAT1 LIG4 MEOX2 NDUFS7 PAXIP1 RPL13A RPL6 SIRPA TST
Entrez ID		6128	4535
HPRD ID		04745	08365
Ensembl ID		ENSG00000089009	ENSG00000198888
Uniprot IDs		A0A024RBK3 Q02878 Q8TBK5	P03886 U5Z754
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO	5XTC 5XTD
Enriched GO Terms of Interacting Partners?
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