RPGR and TSPAN7

Data Source:
HPRD (in vivo)

		RPGR	TSPAN7
Description		retinitis pigmentosa GTPase regulator	tetraspanin 7
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum	Integral Component Of Plasma Membrane
	Molecular Function	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Visual Perception Intraciliary Transport Regulation Of Catalytic Activity Response To Stimulus Cilium Assembly	Viral Process
Pathways			Cell surface interactions at the vascular wall Trafficking of GluR2-containing AMPA receptors
Drugs
Diseases		Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD) Retinitis pigmentosa (RP)	Non-syndromic X-linked mental retardation
GWAS			White blood cell count ( 32888494)
Interacting Genes		14 interacting genes: DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 PDE6D RPGRIP1 SLC25A10 SMC1A SMC3 TUBG1 YWHAE	22 interacting genes: ADRB2 BBS1 BUD31 CACNA1A CCR2 CCR9 CHRM2 CHRM4 CREB3 DRD2 FAM209A FYTTD1 GNRHR GPR152 GPR35 HTR4 LHFPL5 LMNA LTB4R2 MEOX2 OXTR SMO
Entrez ID		6103	7102
HPRD ID		02425	02107
Ensembl ID		ENSG00000156313	ENSG00000156298
Uniprot IDs		Q92834	P41732
PDB IDs		4JHN 4JHP 4QAM
Enriched GO Terms of Interacting Partners?
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