RPGR and SLC25A10

Data Source:
HPRD (in vivo)

		RPGR	SLC25A10
Description		retinitis pigmentosa GTPase regulator	solute carrier family 25 member 10
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum	Nucleus Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding	Dicarboxylic Acid Transmembrane Transporter Activity Protein Binding Sulfate Transmembrane Transporter Activity Thiosulfate Transmembrane Transporter Activity Oxaloacetate Transmembrane Transporter Activity Malate Transmembrane Transporter Activity Succinate Transmembrane Transporter Activity Antiporter Activity
	Biological Process	Intracellular Protein Transport Visual Perception Intraciliary Transport Regulation Of Catalytic Activity Response To Stimulus Cilium Assembly	Gluconeogenesis Ion Transport Dicarboxylic Acid Transport Mitochondrial Transport Sulfate Transport Thiosulfate Transport Oxaloacetate Transport Phosphate Ion Transmembrane Transport Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase Succinate Transmembrane Transport Malate Transmembrane Transport Oxaloacetate(2-) Transmembrane Transport Sulfate Transmembrane Transport
Pathways			Sulfide oxidation to sulfate Organic anion transporters Gluconeogenesis
Drugs
Diseases		Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD) Retinitis pigmentosa (RP)
GWAS			Dental caries ( 23259602) Refractive error ( 32231278)
Interacting Genes		14 interacting genes: DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 PDE6D RPGRIP1 SLC25A10 SMC1A SMC3 TUBG1 YWHAE	10 interacting genes: KRT40 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP4-2 KRTAP5-9 MDFI NOTCH2NLA RBAK RPGR
Entrez ID		6103	1468
HPRD ID		02425	08424
Ensembl ID		ENSG00000156313	ENSG00000183048
Uniprot IDs		Q92834	A0A0S2Z382 A0A0S2Z3G3 B4E1E9 F6RGN5 Q9UBX3
PDB IDs		4JHN 4JHP 4QAM
Enriched GO Terms of Interacting Partners?
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