RGS1 and GDE1

Data Source:
HPRD (two hybrid)

		RGS1	GDE1
Description		regulator of G protein signaling 1	glycerophosphodiester phosphodiesterase 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Plasma Membrane Integral Component Of Membrane Cytoplasmic Vesicle Membrane
	Molecular Function	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Calmodulin Binding	Lysophospholipase Activity Protein Binding Glycerophosphodiester Phosphodiesterase Activity Metal Ion Binding Glycerophosphoinositol Glycerophosphodiesterase Activity
	Biological Process	Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Response To Bacterium Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity Leukotriene Signaling Pathway	Ethanolamine Metabolic Process Lipid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Catabolic Process N-acylethanolamine Metabolic Process
Pathways		G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events	Glycerophospholipid catabolism
Drugs
Diseases
GWAS		Celiac disease ( 22057235 20190752 30572963 18311140) Multiple sclerosis ( 24076602 21833088 27386562) Systemic lupus erythematosus ( 33536424 28714469)
Interacting Genes		9 interacting genes: APP FBXO7 FUNDC2 GDE1 GIPC1 GNAO1 MAP3K12 TSC22D1 UTP14A	7 interacting genes: ADRA1A CLGN RGS1 RGS16 RGS19 RGS2 SLC10A1
Entrez ID		5996	51573
HPRD ID		15968	12070
Ensembl ID		ENSG00000090104	ENSG00000006007
Uniprot IDs		Q08116	A0A024QYU1 Q9NZC3
PDB IDs		2BV1 2GTP
Enriched GO Terms of Interacting Partners?
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