GDE1 and RGS1

Data Source:
HPRD (two hybrid)

		GDE1	RGS1
Description		glycerophosphodiester phosphodiesterase 1	regulator of G protein signaling 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Cytoplasmic Vesicle Membrane	Cytosol Plasma Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Lysophospholipase Activity Protein Binding Glycerophosphodiester Phosphodiesterase Activity Metal Ion Binding Glycerophosphoinositol Glycerophosphodiesterase Activity	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Calmodulin Binding
	Biological Process	Ethanolamine Metabolic Process Lipid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Catabolic Process N-acylethanolamine Metabolic Process	Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Response To Bacterium Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity Leukotriene Signaling Pathway
Pathways		Glycerophospholipid catabolism	G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS			Celiac disease ( 22057235 20190752 30572963 18311140) Multiple sclerosis ( 24076602 21833088 27386562) Systemic lupus erythematosus ( 33536424 28714469)
Interacting Genes		7 interacting genes: ADRA1A CLGN RGS1 RGS16 RGS19 RGS2 SLC10A1	9 interacting genes: APP FBXO7 FUNDC2 GDE1 GIPC1 GNAO1 MAP3K12 TSC22D1 UTP14A
Entrez ID		51573	5996
HPRD ID		12070	15968
Ensembl ID		ENSG00000006007	ENSG00000090104
Uniprot IDs		A0A024QYU1 Q9NZC3	Q08116
PDB IDs			2BV1 2GTP
Enriched GO Terms of Interacting Partners?
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