RGR and RDH5

Data Source:
HPRD (in vivo)

		RGR	RDH5
Description		retinal G protein coupled receptor	retinol dehydrogenase 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Integral Component Of Plasma Membrane	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Membrane Cell Body
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Photoreceptor Activity	Retinol Dehydrogenase Activity Protein Homodimerization Activity Androsterone Dehydrogenase Activity Androstan-3-alpha,17-beta-diol Dehydrogenase Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Visual Perception Phototransduction Detection Of Visible Light Protein-chromophore Linkage Cellular Response To Light Stimulus	Retinoid Metabolic Process Visual Perception Steroid Metabolic Process Retinol Metabolic Process Response To Stimulus
Pathways		G alpha (i) signalling events Opsins	Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision) RA biosynthesis pathway
Drugs			NADH Vitamin A
Diseases		Retinitis pigmentosa (RP)	Familial flecked retina syndrome, including: Doyne honeycomb degeneration of retina (DHRD); Basal laminar drusen (BLD); Fundus albipunctatus (FA); Retinitis punctata albescens (RPA); Bietti crystalline corneoretinal dystrophy (BCD)
GWAS		High myopia ( 31816047) Myopia ( 27182965) Refractive error ( 32231278)	Advanced age-related macular degeneration ( 26691988) High myopia ( 31816047) Macular thickness ( 30535121) Myopia ( 27182965) Refractive error ( 23396134) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		7 interacting genes: ADRB2 CCR2 F2RL1 KIFBP RDH5 TRIM55 TRIM63	3 interacting genes: ORC4 RGR RLBP1
Entrez ID		5995	5959
HPRD ID		02642	03370
Ensembl ID		ENSG00000148604	ENSG00000135437
Uniprot IDs		A0A0S2Z494 A0A0S2Z498 P47804	A0A024RB18 Q92781
PDB IDs
Enriched GO Terms of Interacting Partners?
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