OPN1LW and PIAS3

Data Source:
HPRD (in vitro, in vivo)

		OPN1LW	PIAS3
Description		opsin 1, long wave sensitive	protein inhibitor of activated STAT 3
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Integral Component Of Plasma Membrane Photoreceptor Disc Membrane	Nucleoplasm Cytoplasm Nuclear Speck Dendrite Synapse
	Molecular Function	Protein Binding G Protein-coupled Photoreceptor Activity Photoreceptor Activity	RNA Polymerase II Transcription Factor Binding Transcription Coregulator Activity Protein Binding Protein C-terminus Binding Zinc Ion Binding Potassium Channel Regulator Activity SUMO Transferase Activity Enzyme Binding Protein N-terminus Binding SUMO Ligase Activity
	Biological Process	Retinoid Metabolic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Visual Perception Phototransduction Detection Of Visible Light Protein-chromophore Linkage Positive Regulation Of Cytokinesis Cellular Response To Light Stimulus	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Response To Hormone Positive Regulation Of Gene Expression Protein Sumoylation Negative Regulation Of Protein Sumoylation Positive Regulation Of Protein Sumoylation Negative Regulation Of Osteoclast Differentiation Positive Regulation Of Membrane Potential TNFSF11-mediated Signaling Pathway
Pathways			SUMOylation of transcription factors SUMOylation of transcription cofactors SUMOylation of intracellular receptors SUMOylation of DNA replication proteins SUMOylation of immune response proteins Formation of Incision Complex in GG-NER
Drugs
Diseases		Colorblindness, including: Dichromacy; Anomalous trichromacy Blue cone monochromacy
GWAS		Lymphocyte counts ( 32888494) Monocyte count ( 32888494)
Interacting Genes		6 interacting genes: NCOA2 NRM PIAS3 RANBP2 TICAM2 TRARG1	55 interacting genes: AR ATF7IP CARHSP1 CBS CREBBP CREM EP300 ESR1 ESR2 GEMIN4 GFI1 GLUL HABP4 HDAC1 HMGA2 MITF NCOA2 NR3C2 OPN1LW PGR PLIN3 PPP1CA PRPF40A PSMC1 RAC1 RELA REX1BD SATB1 SENP1 SERBP1 SERPINA10 SIAH1 SIAH2 SKIL SMAD2 SMAD3 SMAD4 SNAI2 SNIP1 SPOP SREBF2 STAT3 SUMO1 SUMO2 SUMO3 TBP TRIM27 TRIM32 TRIM55 TRIM63 UBA1 UBE2I ZFHX3 ZMIZ1 ZMIZ2
Entrez ID		5956	10401
HPRD ID		02366	09068
Ensembl ID		ENSG00000102076	ENSG00000131788
Uniprot IDs			B3KNI3 Q9Y6X2
PDB IDs			4MVT
Enriched GO Terms of Interacting Partners?
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