GNB4 and GNG10

Data Source:
BioGRID (pull down)

		GNB4	GNG10
Description		G protein subunit beta 4	G protein subunit gamma 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Cytosol Heterotrimeric G-protein Complex Extracellular Exosome	Heterotrimeric G-protein Complex Plasma Membrane G-protein Beta/gamma-subunit Complex
	Molecular Function	Protein Binding G-protein Gamma-subunit Binding Protein-containing Complex Binding	GTPase Activity Protein Binding G-protein Beta-subunit Binding
	Biological Process	Protein Folding G Protein-coupled Receptor Signaling Pathway Substantia Nigra Development	Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways		Activation of G protein gated Potassium channels Glucagon signaling in metabolic regulation G-protein activation Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling ADORA2B mediated anti-inflammatory cytokines production Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Activation of G protein gated Potassium channels Glucagon signaling in metabolic regulation G-protein activation Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling ADORA2B mediated anti-inflammatory cytokines production Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Heart rate ( 23583979) Resting heart rate ( 29769521 27798624)
Interacting Genes		18 interacting genes: GNAI1 GNAI2 GNAI3 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 MTNR1A MTNR1B PTEN	9 interacting genes: GNB1 GNB2 GNB3 GNB4 KRT16 KRT31 KRT34 KRT38 TCF4
Entrez ID		59345	2790
HPRD ID		09973	10374
Ensembl ID		ENSG00000114450	ENSG00000242616
Uniprot IDs		Q9HAV0	A0A024R156 P50151
PDB IDs
Enriched GO Terms of Interacting Partners?
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