SELENOK and IL10RA

Data Source:
BioGRID (two hybrid)

		SELENOK	IL10RA
Description		selenoprotein K	interleukin 10 receptor subunit alpha
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane	Cytosol Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity
	Biological Process	Positive Regulation Of Defense Response To Virus By Host Calcium Ion Transport Response To Oxidative Stress Macrophage Derived Foam Cell Differentiation Protein Palmitoylation Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of T Cell Proliferation Respiratory Burst After Phagocytosis Regulation Of Calcium-mediated Signaling Regulation Of Protein Transport Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Positive Regulation Of Monocyte Chemotactic Protein-1 Production Positive Regulation Of T Cell Migration	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Synapse Organization Ubiquitin-dependent Endocytosis
Pathways			Interleukin-10 signaling
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Interacting Genes		38 interacting genes: AMIGO1 AQP6 BIK C6orf47 CLN8 CNR2 COMT CPLX4 CREB3 ERBB2 ERBB3 ERBB4 ERGIC3 FAM209A FFAR2 GLP1R GORAB GPR35 GPX8 IL10RA KLHDC2 LMNA MFSD6 MMD MRM1 MTIF3 MUC1 REEP4 RNF19B SLC10A1 SLC30A8 SLC35C2 SLC35E3 STMN4 STOM TMEM31 TMPRSS2 TMX2	20 interacting genes: BTRC C1QL4 CDS2 CMTM3 HACD1 IL10 IL10RB JAK1 MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6
Entrez ID		58515	3587
HPRD ID		07448	00911
Ensembl ID		ENSG00000113811	ENSG00000110324
Uniprot IDs		Q9Y6D0	Q13651
PDB IDs		6DO3	1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI
Enriched GO Terms of Interacting Partners?
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