PTBP2 and QKI

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		PTBP2	QKI
Description		polypyrimidine tract binding protein 2	QKI, KH domain containing RNA binding
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GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Growth Cone Neuronal Cell Body	Nucleus Cytoplasm Synapse
	Molecular Function	RNA Binding MRNA Binding	RNA Binding MRNA Binding Protein Binding SH3 Domain Binding
	Biological Process	MRNA Splice Site Selection Spinal Cord Development Cerebellum Development Negative Regulation Of RNA Splicing Regulation Of RNA Splicing Regulation Of Neural Precursor Cell Proliferation	Vasculogenesis MRNA Processing Regulation Of Translation Spermatid Development RNA Splicing Positive Regulation Of Gene Expression Myelination Muscle Cell Differentiation Long-chain Fatty Acid Biosynthetic Process Regulation Of MRNA Splicing, Via Spliceosome MRNA Transport
Pathways			Signaling by BRAF and RAF fusions
Drugs
Diseases
GWAS		Adult body size ( 32376654) Anorexia nervosa ( 31308545) Autism spectrum disorder ( 30804558) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically inactive individuals ( 28448500) Body size at age 10 ( 32376654) Chronotype ( 30696823) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) Headache ( 29397368) Hip circumference ( 25673412) Number of sexual partners ( 30643258) Reaction time ( 29844566) Regular attendance at a pub or social club ( 29970889) Schizophrenia ( 19571811 22688191) Smoking status (ever vs never smokers) ( 30643258) Trunk fat mass adjusted for trunk lean mass ( 32239398 30944420) Waist circumference ( 25673412)	Diastolic blood pressure ( 27841878) Diisocyanate-induced asthma ( 25918132) Height ( 31562340) Hemoglobin ( 32888494) Incident myocardial infarction ( 26950853) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Platelet distribution width ( 32888494) Red blood cell count ( 29403010) Refractive error ( 32231278) Response to TNF antagonist treatment ( 18615156) Seasonality and depression ( 30217971) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969 30718926)
Interacting Genes		19 interacting genes: CALCOCO2 EIF5A2 ELAVL1 GOLGA2 HNRNPAB HNRNPC HNRNPD KHDRBS1 KHDRBS3 KHSRP MATR3 PCBP3 PUF60 QKI RBM10 RBM4 RBPMS2 SNRPA TOM1	50 interacting genes: APP ATXN1 CARM1 CCND3 CDKN2D DAZ1 DAZ4 DEPP1 DMRTB1 FBXO7 FHL3 FUBP3 HCLS1 HNRNPH2 HNRNPK IL7R LSM3 MIR141 MIR19B2 MIR200A MIR34B MIR34C MIR7-1 NABP1 PCBP1 PCBP2 PCBP4 PIAS1 PRKAB2 PRMT1 PSMF1 PTBP1 PTBP2 RALY RBFOX1 RBFOX2 RBM11 RBM14 RBM23 RBPMS RNF138 SERF2 SNRPA TEX11 THAP1 TIAL1 TSG101 U2AF2 USH1C WDR77
Entrez ID		58155	9444
HPRD ID		12233	06691
Ensembl ID		ENSG00000117569	ENSG00000112531
Uniprot IDs		A0A6Q8PFE6 B4DSS8 B4DSU5 Q9UKA9	Q8WY44 Q96PU8
PDB IDs		2CQ1 2MJU 4CQ1	4JVH
Enriched GO Terms of Interacting Partners?
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