NCOA5 and KHDRBS3

Data Source:
BioGRID (two hybrid)

		NCOA5	KHDRBS3
Description		nuclear receptor coactivator 5	KH RNA binding domain containing, signal transduction associated 3
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GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Actin Cytoskeleton	Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	Chromatin Binding Transcription Corepressor Activity RNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding SH3 Domain Binding Protein Domain Specific Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Glucose Homeostasis Negative Regulation Of Insulin Receptor Signaling Pathway	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Viral Process Regulation Of MRNA Splicing, Via Spliceosome
Pathways			PTK6 Regulates Proteins Involved in RNA Processing
Drugs		17alpha-Estriol
Diseases
GWAS		Crohn's disease ( 28067908) Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831) Follicular lymphoma or multiple sclerosis ( 31407831) HDL cholesterol levels ( 32203549) Hodgkin's lymphoma ( 30194254) Inflammatory bowel disease ( 28067908) Marginal zone lymphoma or multiple sclerosis ( 31407831) Multiple sclerosis ( 31604244 21833088) Systemic lupus erythematosus ( 28714469) Tonsillectomy ( 27182965 28928442)	Chronotype ( 30696823) Disease progression in age-related macular degeneration ( 29346644) Polycystic ovary syndrome ( 25574032) Squamous cell lung carcinoma ( 28604730) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		19 interacting genes: ACOT7 CCDC57 CDC37 FAM214B GORASP2 HTATIP2 KANK2 KHDRBS2 KHDRBS3 MEIG1 NR1D2 NTAQ1 PICK1 RAB30 SYT16 TSC22D1 TSGA10IP UBL5 ZNF326	54 interacting genes: AQP1 BAHD1 CACNA1A CCDC187 CCDC33 CNNM3 DMRT3 DOCK2 FBXO7 FUS HBZ HNRNPC HNRNPK INPP5D KHDRBS1 KHDRBS2 LMNTD2 LNX1 MARK4 MYPOP NCOA5 NELFB NUDT18 PCDHB14 PPP1R13B PRMT1 PRPF31 PRR3 PSMA1 PSMF1 PTBP2 RASAL3 RASD1 RBBP6 RBM3 RBM7 RBMX RBMY1A1 RFC3 RPH3AL SGSM2 SIAH1 SNRPC SNX18 SRSF9 TSGA10IP TYK2 U2AF2 YTHDC1 ZNF326 ZNF408 ZNF575 ZNF580 ZNF688
Entrez ID		57727	10656
HPRD ID		14813	10007
Ensembl ID		ENSG00000124160	ENSG00000131773
Uniprot IDs		Q9HCD5	O75525
PDB IDs		1V95 2J7X 2J7Y 4ZI1	5EL3 5ELR 5ELS 5ELT 5EMO
Enriched GO Terms of Interacting Partners?
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